Evidence map›Paper›PMID 32823634›Full record

ArticleInternational journal of molecular sciences2020

Reduction of Allergenic Potential in Bread Wheat RNAi Transgenic Lines Silenced for

Raviraj M Kalunke, Silvio Tundo, Francesco Sestili, Francesco Camerlengo, Domenico Lafiandra, Roberta Lupi, Colette Larré, Sandra Denery-Papini, Shahidul Islam, Wujun Ma and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

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  12. Plant Proteomic Research 3.0: Challenges and Perspectives.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 5 countries.

Raviraj M KalunkeDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0003-0110-2888
Silvio TundoDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-3638-7345
Francesco SestiliDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0002-9653-8002
Francesco CamerlengoDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.
Domenico LafiandraDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.
Roberta LupiINRAE UR1268 BIA, 44000 Nantes, France.
Colette LarréINRAE UR1268 BIA, 44000 Nantes, France.ORCID 0000-0001-9585-9536
Sandra Denery-PapiniINRAE UR1268 BIA, 44000 Nantes, France.ORCID 0000-0002-9692-021X
Shahidul IslamAustralia China Centre for Wheat Improvement, College of Science Health Engineering and Education, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0001-5994-0521
Wujun MaAustralia China Centre for Wheat Improvement, College of Science Health Engineering and Education, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0002-1264-866X
Stefano D'AmicoInstitute for Animal Nutrition and Feed, AGES-Austrian Agency for Health and Food Safety, 1220 Vienna, Austria.ORCID 0000-0002-6702-7158
Stefania MasciDepartment of Agriculture and Forest Science (DAFNE), University of Tuscia, 01100 Viterbo, Italy.ORCID 0000-0003-2857-4498
Università degli Studi della Tuscia · ITInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRMurdoch University · AUAustrian Agency for Health and Food Safety · ATUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although wheat is used worldwide as a staple food, it can give rise to adverse reactions, for which the triggering factors have not been identified yet. These reactions can be caused mainly by kernel proteins, both gluten and non-gluten proteins. Among these latter proteins, α-amylase/trypsin inhibitors (ATI) are involved in baker's asthma and realistically in Non Celiac Wheat Sensitivity (NCWS). In this paper, we report characterization of three transgenic lines obtained from the bread wheat cultivar Bobwhite silenced by RNAi in the three ATI genes

Indexed as

BreadGenes, PlantRNA InterferenceAllergensalpha-AmylasesGene Expression Regulation, PlantHumansHypersensitivityImmunoglobulin EPlant ProteinsPlants, Genetically ModifiedProtein BindingSolubilityTransformation, GeneticTriticumAllergensalpha-AmylasesImmunoglobulin EPlant Proteinsallergynon celiac wheat sensitivity (NCWS)RNAi silencingwheatα-amylase/trypsin inhibitor (ATI)

Identifiers

PMID32823634
PMCPMC7461106
OpenAlexW3044493277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.