ArticleInternational journal of environmental research and public health2020
Time Course of Autonomic Symptoms in Postural Orthostatic Tachycardia Syndrome (POTS) Patients: Two-Year Follow-Up Results.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Long-term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow-up of over 20 years.Journal of internal medicine · 2026Article
- Short and long term effects of a two-week transcutaneous vagus nerve stimulation in hyperadrenergic postural orthostatic tachycardia syndrome: a proof-of-concept trial.European journal of internal medicine · 2026Article
- The Diagnostic Journey of Dysautonomia Patients: Insights from a Patient-Reported Outcome Study.Journal of patient experience · 2025Article
- Article
- Invalidated and 'salty': an auto/biographical and theoretical review of the lived experiences of individuals with PoTS.Frontiers in sociology · 2024Article
- Cardiovascular, autonomic symptoms and quality of life in children with hypermobile Ehlers-Danlos syndrome.SAGE open medicine · 2024Article
- Cardiovascular Symptoms, Dysautonomia, and Quality of Life in Adult and Pediatric Patients with Hypermobile Ehlers-Danlos Syndrome: A Brief Review.Current cardiology reviews · 2024Review
- Malmö POTS symptom score: Assessing symptom burden in postural orthostatic tachycardia syndrome.Journal of internal medicine · 2023Article
- Autonomic dysfunction after moderate-to-severe traumatic brain injury: symptom spectrum and clinical testing outcomes.BMJ neurology open · 2022Article
- Brain fog in neuropathic postural tachycardia syndrome may be associated with autonomic hyperarousal and improves after water drinking.Frontiers in neuroscience · 2022Article
- Transdermal auricular vagus stimulation for the treatment of postural tachycardia syndrome.Autonomic neuroscience : basic & clinical · 2021Article
- Relationships Between Cardiovascular Autonomic Profile and Work Ability in Patients With Pure Autonomic Failure.Frontiers in human neuroscience · 2021Article
- COVID-19 Dysautonomia.Frontiers in neurology · 2021Article
- Work Ability Assessment and Its Relationship with Cardiovascular Autonomic Profile in Postural Orthostatic Tachycardia Syndrome.International journal of environmental research and public health · 2020Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postural orthostatic tachycardia syndrome (POTS) is a multifactorial condition capable of chronically reducing the quality of life and the work ability of patients. The study aim was to assess the burden of autonomic symptoms in a cohort of POTS patients over 2 years. Patients' clinical profiles were assessed by the 31-item Composite Autonomic Symptom Score questionnaire (COMPASS 31) and a visual analog scale (VAS). One-way ANOVA for repeated measures followed by Dunnett's post-hoc test were used to compare symptoms at baseline and at 1 and 2 years. Out of 42 enrolled patients, 25 had a 1-year follow-up and 12 had a 2-year follow-up. At baseline, the reported burden of autonomic symptoms was high (overall COMPASS 31 = 49.9 ± 14.3 /100). Main complaints were related to orthostatic intolerance according to both COMPASS 31 and VAS. Fourteen patients were rendered inactive because of symptoms. At 1-year follow-up, a statistically significant improvement in pupillomotor function and overall score was detected by the COMPASS 31. These findings were confirmed at 2 years, together with a significant reduction in quality of life impairment, assessed by VAS. However, these improvements did not change patients' occupational status. Awareness of POTS diagnosis, patient monitoring, and tailored therapies can help to improve patients' condition.
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