Evidence map›Paper›PMID 32823562›Full record

ReviewNutrients2020

Diet, Stress and Mental Health.

J Douglas Bremner, Kasra Moazzami, Matthew T Wittbrodt, Jonathon A Nye, Bruno B Lima, Charles F Gillespie, Mark H Rapaport, Bradley D Pearce, Amit J Shah, Viola Vaccarino

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 213 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
213citing papers in PubMed, 10 pooled it
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05758311 unknown statusnot on this mapstarted 2024, after this paper: background citation

Adipose Tissue & Adipokines (ATA): From Laboratory to Clinical Practice - The Project ATA

TypeobservationalSponsorDynamical Business and Science Society - DBSS International SASRan2024 to 2024Enrolled378ConditionsSedentary Behavior, Overweight, Obesity
NCT07489664 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Indigenous Nutritional Supplements for Pregnancy to Improve Resilience in Environmental Heat

TypeinterventionalSponsorAga Khan UniversityRan2026 to 2028Enrolled292ConditionsHeat Stress, Pregnancy, Women of Reproductive Age, Nutrition StatusArmsIndigenous Balanced Diet Arm
3 · Its place in the literature

Who cites it

213 citing papers in PubMed, 10 syntheses or guidelines pooled it, 352 citations in OpenAlex.

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153 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

J Douglas BremnerDepartments of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.ORCID 0000-0003-1633-6433
Kasra MoazzamiDepartment of Medicine (Cardiology), Emory University School of Medicine, Atlanta, GA 30332, USA.
Matthew T WittbrodtDepartments of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.ORCID 0000-0002-9533-8041
Jonathon A NyeDepartment of Radiology, Emory University School of Medicine, Atlanta, GA 30332, USA.
Bruno B LimaDepartment of Medicine (Cardiology), Emory University School of Medicine, Atlanta, GA 30332, USA.
Charles F GillespieDepartments of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.
Mark H RapaportDepartments of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30329, USA.
Bradley D PearceDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Amit J ShahAtlanta VA Medical Center, Decatur, GA 30033, USA.
Viola VaccarinoDepartment of Medicine (Cardiology), Emory University School of Medicine, Atlanta, GA 30332, USA.
Emory University · US

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2010 to 2015
$11.0M
J: NRSA Training CoreTL1TR002382 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Vasiliki Michopoulos · 2017 to 2026
$8.5M
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisR01HL109413 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2012 to 2023
$6.9M
Neural Circuits in Women with Abuse and PTSDR01MH056120 · NIMH · YALE UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 1999 to 2011
$5.0M
Mechanisms Linking Depression to Cardiovascular RiskR01HL068630 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2001 to 2010
$4.8M
PTSD and Ischemic Heart Disease Progression: A Longitudinal Twin StudyR01HL125246 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2015 to 2018
$3.4M
Dopamine function, inflammation and connectivity in PTSDR01MH120262 · NIMH · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2020 to 2023
$2.9M
Mechanisms of Depression in CVDR01HL088726 · NHLBI · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2008 to 2012
$2.6M
Mind-Body Interactions in Cardiovascular DiseaseK24HL077506 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2004 to 2013
$1.5M
Biological Correlates of Traumatic StressK24MH076955 · NIMH · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS · 2006 to 2013
$946k
Non-Invasive Vagal Nerve Stimulation in Patients with Opioid Use Disorders UG3DA048502 · NIDA · EMORY UNIVERSITY · PI BREMNER, JAMES DOUGLAS, INAN, OMER TOLGA · 2020 to 2021
$844k
NCATS NIH HHS TL1 TR002382NCATS NIH HHS UL1 TR002378NCRR NIH HHS S10 RR16917NHLBI NIH HHS K23 HL127251NHLBI NIH HHS K24 HL077506NHLBI NIH HHS P01 HL101398NHLBI NIH HHS R01 HL068630NHLBI NIH HHS R01 HL088726NHLBI NIH HHS R01 HL109413NHLBI NIH HHS R01 HL125246NIDA NIH HHS UG3 DA048502NIMH NIH HHS K24 MH076955NIMH NIH HHS R01 MH056120NIMH NIH HHS R01 MH120262NIMH NIH HHS T32 MH067547RRD VA I01 RX003418
6 · The paper itself

Abstract

introductionThere has long been an interest in the effects of diet on mental health, and the interaction of the two with stress; however, the nature of these relationships is not well understood. Although associations between diet, obesity and the related metabolic syndrome (MetS), stress, and mental disorders exist, causal pathways have not been established.

methodsWe reviewed the literature on the relationship between diet, stress, obesity and psychiatric disorders related to stress.

resultsDiet and obesity can affect mood through direct effects, or stress-related mental disorders could lead to changes in diet habits that affect weight. Alternatively, common factors such as stress or predisposition could lead to both obesity and stress-related mental disorders, such as depression and posttraumatic stress disorder (PTSD). Specific aspects of diet can lead to acute changes in mood as well as stimulate inflammation, which has led to efforts to assess polyunsaturated fats (PUFA) as a treatment for depression. Bidirectional relationships between these different factors are also likely. Finally, there has been increased attention recently on the relationship between the gut and the brain, with the realization that the gut microbiome has an influence on brain function and probably also mood and behavior, introducing another way diet can influence mental health and disorders. Brain areas and neurotransmitters and neuropeptides that are involved in both mood and appetite likely play a role in mediating this relationship.

conclusionsUnderstanding the relationship between diet, stress and mood and behavior could have important implications for the treatment of both stress-related mental disorders and obesity.

Indexed as

Mental HealthAffectBrainDepressionDietFatty Acids, UnsaturatedGastrointestinal MicrobiomeHumansMental DisordersNeuropeptidesNeurotransmitter AgentsObesityStress Disorders, Post-TraumaticStress, PsychologicalFatty Acids, UnsaturatedNeuropeptidesNeurotransmitter Agentsbraincardiovascular diseasechild abusecoronary artery diseasedepressive disorderdietgalaninghrelinMediterranean dietmetabolic syndromemicrobiomemyocardial ischemianutritionobesityposttraumaticserotoninsomatostatinstress disorders

Identifiers

PMID32823562
PMCPMC7468813
OpenAlexW3048544321

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.