Evidence map›Paper›PMID 32823525›Full record

ArticleInternational journal of environmental research and public health2020

Transcriptional Profiling and Biological Pathway(s) Analysis of Type 2 Diabetes Mellitus in a Pakistani Population.

Zarish Noreen, Christopher A Loffredo, Attya Bhatti, Jyothirmai J Simhadri, Gail Nunlee-Bland, Thomas Nnanabu, Peter John, Jahangir S Khan, Somiranjan Ghosh

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Zarish NoreenHealthCare Biotechnology, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.
Christopher A LoffredoDepartments of Oncology and of Biostatistics, Georgetown University, Washington, DC 20057, USA.
Attya BhattiHealthCare Biotechnology, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.
Jyothirmai J SimhadriDepartment of Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC 20059, USA.
Gail Nunlee-BlandDepartment of Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC 20059, USA.ORCID 0000-0001-6388-688X
Thomas NnanabuDepartment of Biology, Howard University, Washington, DC 20059, USA.
Peter JohnHealthCare Biotechnology, Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology (NUST), Islamabad 44000, Pakistan.
Jahangir S KhanDepartment of Surgery, Rawalpindi Medical College, Rawalpindi, Punjab 46000, Pakistan.
Somiranjan GhoshDepartment of Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC 20059, USA.ORCID 0000-0002-5280-7418
Howard University · USNational University of Sciences and Technology · PKGeorgetown University · USRawalpindi Medical University · PK

Funding

Sleep Disorders in Adults with Sickle Cell Disease: Frequency, Associations with Cardiovascular and Pain Indicators, and Responses to TreatmentU54MD007597 · NIMHD · HOWARD UNIVERSITY · PI Tatiana V.D. Sanses · 2019 to 2026
$37.7M
NCI NIH HHS 1-P20 CA262617-01NIMHD NIH HHS 2-U54 MD00759731NIMHD NIH HHS U54 MD007597
6 · The paper itself

Abstract

The epidemic of type 2 diabetes mellitus (T2DM) is an important global health concern. Our earlier epidemiological investigation in Pakistan prompted us to conduct a molecular investigation to decipher the differential genetic pathways of this health condition in relation to non-diabetic controls. Our microarray studies of global gene expression were conducted on the Affymetrix platform using Human Genome U133 Plus 2.0 Array along with Ingenuity Pathway Analysis (

Indexed as

Diabetes Mellitus, Type 2Gene Expression ProfilingGlucose Transport Proteins, FacilitativeHumansPakistanPilot Projectsras ProteinsTranscriptomeGlucose Transport Proteins, Facilitativeras Proteinsbiomarkersdisease pathwaysgene expressiongene validationPakistantype 2 diabetes

Identifiers

PMID32823525
PMCPMC7460550
OpenAlexW3048442300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.