Evidence map›Paper›PMID 32823472›Full record

ArticleIndian journal of ophthalmology2020

Correlation of vascular endothelial growth factor with the clinical regression of tubercular granuloma.

Manisha Agarwal, Chanda Gupta, K Varsha Mohan, Pramod K Upadhyay, Vivek Jha

Abstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Bilateral choroidal tuberculoma in a patient of miliary tuberculosis.Journal of ophthalmic inflammation and infection · 2025
    Article
  3. Correlation of angiogenic growth factors and inflammatory cytokines with the clinical phenotype of ocular tuberculosis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Article
  4. Tuberculosis pathophysiology and anti-VEGF intervention.Journal of clinical tuberculosis and other mycobacterial diseases · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manisha AgarwalDepartment of Vitreoretina services, Dr Shroff's Charity Eye Hospital, New Delhi, India.
Chanda GuptaDepartment of Vitreoretina services, Dr Shroff's Charity Eye Hospital, New Delhi, India.
K Varsha MohanNational Institute of Immunology, New Delhi, India.
Pramod K UpadhyayNational Institute of Immunology, New Delhi, India.
Vivek JhaDepartment of Vitreoretina services, Dr Shroff's Charity Eye Hospital, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tubercular granulomas are a common manifestation of intraocular tuberculosis. These are said to be hypoxic granulomas with increased expression of vascular endothelial growth factor (VEGF). Management of these granulomas includes a combination of antitubercular therapy (ATT) and oral corticosteroids. We report a case of tubercular granuloma with exudative retinal detachment which was treated with weekly intravitreal anti-VEGF and antibiotic injections along with ATT and corticosteroids. The VEGF levels measured paralleled with the clinical regression of the granuloma.

Indexed as

Angiogenesis InhibitorsVascular Endothelial Growth Factor ABevacizumabGranulomaHumansIntravitreal InjectionsRanibizumabVascular Endothelial Growth FactorsAngiogenesis InhibitorsBevacizumabRanibizumabVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsAnti-VEGF drugbevacizumabtubercular granulomavascular endothelial growth factorVEGF

Identifiers

PMID32823472
PMCPMC7690512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.