ArticleMagnetic resonance imaging2020
10.5 T MRI static field effects on human cognitive, vestibular, and physiological function.
Article in Magnetic resonance imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Mesoscale Whole-Brain TMagnetic resonance in medicine · 2026Article
- 10.5 T In Vivo Head Imaging With Universal RF Shimming.Magnetic resonance in medicine · 2026Article
- Advancing whole-brain BOLD functional MRI in humans at 10.5 T with motion-robust 3D echo-planar imaging, parallel transmission, and high-density radiofrequency receive coils.Magnetic resonance in medicine · 2026Article
- A 128-channel receive array with enhanced signal-to-noise ratio performance for 10.5T brain imaging.Magnetic resonance in medicine · 2025Article
- Exploring in vivo human brain metabolism at 10.5 T: Initial insights from MR spectroscopic imaging.NeuroImage · 2025Article
- RF coil design strategies for improving SNR at the ultrahigh magnetic field of 10.5T.Magnetic resonance in medicine · 2025Article
- In vivo imaging of the human brain with the Iseult 11.7-T MRI scanner.Nature methods · 2024Article
- Performance of receive head arrays versus ultimate intrinsic SNR at 7 T and 10.5 T.Magnetic resonance in medicine · 2024Article
- Changes in tissue sodium concentration and sodium relaxation times during the maturation of human knee cartilage: Ex vivoMagnetic resonance in medicine · 2024Article
- Radiofrequency antenna concepts for human cardiac MR at 14.0 T.Magma (New York, N.Y.) · 2023Article
- Germany's journey toward 14 Tesla human magnetic resonance.Magma (New York, N.Y.) · 2023Review
- The Promise of Magnetic Resonance Imaging in Radiation Oncology Practice in the Management of Brain, Prostate, and GI Malignancies.JCO global oncology · 2022Review
- Occupational exposure to electromagnetic fields in magnetic resonance environment: an update on regulation, exposure assessment techniques, health risk evaluation, and surveillance.Medical & biological engineering & computing · 2022Review
- Article
- 7 Tesla and Beyond: Advanced Methods and Clinical Applications in Magnetic Resonance Imaging.Investigative radiology · 2021Review
- Non-Invasive Analysis of Human Liver Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2021Review
- Long-term behavioral effects observed in mice chronically exposed to static ultra-high magnetic fields.Magnetic resonance in medicine · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo perform a pilot study to quantitatively assess cognitive, vestibular, and physiological function during and after exposure to a magnetic resonance imaging (MRI) system with a static field strength of 10.5 Tesla at multiple time scales.
methodsA total of 29 subjects were exposed to a 10.5 T MRI field and underwent vestibular, cognitive, and physiological testing before, during, and after exposure; for 26 subjects, testing and exposure were repeated within 2-4 weeks of the first visit. Subjects also reported sensory perceptions after each exposure. Comparisons were made between short and long term time points in the study with respect to the parameters measured in the study; short term comparison included pre-vs-isocenter and pre-vs-post (1-24 h), while long term compared pre-exposures 2-4 weeks apart.
resultsOf the 79 comparisons, 73 parameters were unchanged or had small improvements after magnet exposure. The exceptions to this included lower scores on short term (i.e. same day) executive function testing, greater isocenter spontaneous eye movement during visit 1 (relative to pre-exposure), increased number of abnormalities on videonystagmography visit 2 versus visit 1 and a mix of small increases (short term visit 2) and decreases (short term visit 1) in blood pressure. In addition, more subjects reported metallic taste at 10.5 T in comparison to similar data obtained in previous studies at 7 T and 9.4 T.
conclusionInitial results of 10.5 T static field exposure indicate that 1) cognitive performance is not compromised at isocenter, 2) subjects experience increased eye movement at isocenter, and 3) subjects experience small changes in vital signs but no field-induced increase in blood pressure. While small but significant differences were found in some comparisons, none were identified as compromising subject safety. A modified testing protocol informed by these results was devised with the goal of permitting increased enrollment while providing continued monitoring to evaluate field effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.