Evidence map›Paper›PMID 32822531›Full record

ArticleBiochemistry2020

Protein Splicing Activity of the

Shachar Robinzon, Alexandra R Cawood, Mercedes A Ruiz, Uri Gophna, Neta Altman-Price, Kenneth V Mills

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Shachar RobinzonThe Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Alexandra R CawoodDepartment of Chemistry, College of the Holy Cross, Worcester, Massachusetts 01610, United States.
Mercedes A RuizDepartment of Chemistry, College of the Holy Cross, Worcester, Massachusetts 01610, United States.
Uri GophnaThe Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Neta Altman-PriceThe Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Kenneth V MillsDepartment of Chemistry, College of the Holy Cross, Worcester, Massachusetts 01610, United States.ORCID 0000-0001-6052-308X
College of the Holy Cross · USTel Aviv University · IL

Funding

The Regulation of Inteins: Adaptations in Extremophiles and Targets for Drug DiscoveryR15GM132817 · NIGMS · COLLEGE OF THE HOLY CROSS · PI MILLS, KENNETH V · 2019 to 2024
$723k
Acquisition of an Orbitrap MSS10OD010645 · OD · UNIVERSITY OF MASSACHUSETTS AMHERST · PI EYLES, STEPHEN J. · 2013 to 2013
$600k
NIGMS NIH HHS R15 GM132817NIH HHS S10 OD010645
6 · The paper itself

Abstract

Inteins are selfish genetic elements residing in open reading frames that can splice post-translationally, resulting in the ligation of an uninterrupted, functional protein. Like other inteins, the DNA polymerase B (PolB) intein of the halophilic archaeon

Indexed as

InteinsMutationProtein SplicingArchaeal ProteinsCatalytic DomainDNA Polymerase betaEndonucleasesHaloferax volcaniiMolecular Dynamics SimulationProtein ConformationArchaeal ProteinsDNA Polymerase betaEndonucleases

Identifiers

PMID32822531
PMCPMC7494616
OpenAlexW3080967151

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.