Evidence map›Paper›PMID 32822371›Full record

ArticlePloS one2020

Morphologic analysis of macular neovascularizations by OCT angiography-Technical limitations in the comparison of 3×3mm and 6×6mm images.

Henrik Faatz, Kai Rothaus, Marie-Louise Gunnemann, Marius Book, Pia Wilming, Matthias Gutfleisch, Georg Spital, Albrecht Lommatzsch, Daniel Pauleikhoff

Abstract readComparative Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Henrik FaatzDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.ORCID 0000-0002-5363-0052
Kai RothausDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Marie-Louise GunnemannDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Marius BookDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Pia WilmingDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Matthias GutfleischDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Georg SpitalDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Albrecht LommatzschDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.
Daniel PauleikhoffDepartment of Ophthalmology, St. Franziskus Hospital, Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to ascertain whether there are relevant differences between the vascular morphology of macular neovascularizations (MNV) in 3×3mm and 6×6mm images, produced by optical coherence tomography angiography (OCTA).

methodsMNV of 49 patients were automated quantitative analysed, measuring area, flow, the fractal dimension, average vessel length, vascular density, and average vessel caliber. These parameters were compared between the 3×3mm and the 6×6mm images.

resultsA strong linear association was found between the 3×3mm and the 6×6mm images. While area, flow, and FD of the MNV were very similar, the 3×3mm images showed significantly lower average total vessel length, greater vascular density, and lower average vessel caliber.

conclusionIn quantitative analysis of the morphologic parameters of MNV in 3×3mm and 6×6mm images, the structures are not directly equivalent in the two sizes of scan. The images must be evaluated on an individual basis.

Indexed as

AgedAged, 80 and overAngiographyFemaleHumansImage Processing, Computer-AssistedMacula LuteaMaleMiddle AgedNeovascularization, PathologicRetinal VesselsTomography, Optical Coherence

Identifiers

PMID32822371
PMCPMC7446777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.