Evidence map›Paper›PMID 32822105›Full record

ArticleJournal of veterinary internal medicine2020

Biomarker changes with systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy.

Joonbum Seo, Jessie Rosie Payne, Jose Novo Matos, Wesley Wynne Fong, David J Connolly, Virginia Luis Fuentes

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  11. The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Joonbum SeoClinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.ORCID https://orcid.org/0000-0002-8215-1237
Jessie Rosie PayneLangford Vets Small Animal Referral Hospital, University of Bristol, Bristol, United Kingdom.
Jose Novo MatosClinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.ORCID https://orcid.org/0000-0001-8128-8111
Wesley Wynne FongClinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.
David J ConnollyClinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.
Virginia Luis FuentesClinical Science and Services, Royal Veterinary College, Hertfordshire, United Kingdom.ORCID https://orcid.org/0000-0001-8076-3806
Royal Veterinary College · GBUniversity of Bristol · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundN-terminal pro B-type natriuretic peptide (NT-proBNP) and cardiac troponin-I (cTnI) are biomarkers commonly evaluated in cats with suspected heart disease. Many cats with hypertrophic cardiomyopathy (HCM) have systolic anterior motion of the mitral valve (SAM), but its influence on circulating NT-proBNP or cTnI concentrations is currently unknown. HYPOTHESIS/

objectivesCats with HCM and SAM (HCM ANIMALS: One hundred forty cats with HCM: 70 with SAM and 70 without SAM.

methodsRetrospective case-to-case study. Cats were recruited if diagnosed with HCM by echocardiography and results were available for NT-proBNP or cTnI concentrations or both. Cats with SAM were matched to those without SAM for clinical presentation, left atrial (LA) size and left ventricular (LV) fractional shortening.

resultsA total of 119 NT-proBNP and 123 cTnI results were available. The HCM CONCLUSIONS AND CLINICAL IMPORTANCE: For cats with HCM and equivalent LA size and LV systolic function, those with SAM had higher NT-proBNP and cTnI concentrations than did those without SAM. Presence of SAM should be considered when interpreting biomarker concentrations in cats with HCM.

Indexed as

Cardiomyopathy, HypertrophicCat DiseasesAnimalsBiomarkersCatsFemaleMaleMitral ValveNatriuretic Peptide, BrainPeptide FragmentsRetrospective StudiesTroponin IBiomarkersNatriuretic Peptide, BrainPeptide FragmentsTroponin Icardiologycatnatriuretic peptideobstructive cardiomyopathytroponin

Identifiers

PMID32822105
PMCPMC7517492
OpenAlexW3080784445

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.