ReviewJournal of magnetic resonance imaging : JMRI2021
Multiparametric MRI in Patients With Nonalcoholic Fatty Liver Disease.
Review in Journal of magnetic resonance imaging : JMRI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05987748 (The Clock Thickens), which is not on this map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Clock Thickens: Morning or Evening Training for the Treatment of NAFLD? (TikTac Study)
Who cites it
43 citing papers in PubMed, 79 citations in OpenAlex.
- Phase-Sensitive Modeling Improves Fat DESPOT Multiparametric Relaxation Mapping in Fat-Water Mixtures.Magnetic resonance in medicine · 2026Article
- Water-T1, PDFF, and T2* mapping of the liver using chemical shift-encoded MOLLI.Abdominal radiology (New York) · 2026Article
- Impact of hepatic steatosis and MOLLI acquisition parameters on liver T1 estimates.Abdominal radiology (New York) · 2026Article
- From Molecular Mechanisms to Clinical Strategies: A Comprehensive Overview of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).International journal of molecular sciences · 2026Review
- Development and internal validation of a noninvasive predictive model based on iron and fat measurements for pathologic risk stratification in prostate cancer.Translational andrology and urology · 2026Article
- Quantitative MR biomarkers in identifying steatohepatitis and fibrosis associated with metabolic dysfunction associated liver disease-a single center cross-sectional study.Abdominal radiology (New York) · 2026Article
- Lymphedema imaging and AI: A review of diagnostic modalities, biomarkers, and clinical integration.Biomedical journal · 2026Review
- Comparison of hepatic PDFF, T2*, and T2 estimates from breath-hold and free-breathing respiratory-gated MRI acquisitions in children and young adults.Abdominal radiology (New York) · 2026Article
- Comparison of hepatic iron quantification by MRI between 1.5 and 3 T, using different methods and conversion formulas.European radiology · 2026Article
- Clinical Application of Magnetic Resonance Imaging in the Diagnosis of NAFLDCurrent medical imaging · 2026Review
- Optimal Segment Selection on Gadoxetic Acid-Enhanced MRI to Improve Diagnostic Accuracy in the Histological Grading of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.Journal of clinical medicine · 2025Article
- Article
- Review
- Real-World Assessment of Liver Corrected T1 and Magnetic Resonance Elastography in Predicting Liver Disease Progression.Liver international : official journal of the International Association for the Study of the Liver · 2025Article
- Automated quantification of T1 and T2 relaxation times in liver mpMRI using deep learning: a sequence-adaptive approach.European radiology experimental · 2025Article
- The correlation between metabolic dysfunction-associated steatotic liver disease (MASLD) grades and hemodynamic alterations of the portal, hepatic, and splenic vein and spleen size.Journal of ultrasound · 2025Article
- Simultaneous Multiparameter Mapping of the Liver in a Single Breath-Hold or Respiratory-Triggered Acquisition Using Multi-Inversion Spin and Gradient Echo MRI.Journal of magnetic resonance imaging : JMRI · 2025Article
- Influence of fat on hepatic T2 relaxation time estimation: a preliminary investigation.Abdominal radiology (New York) · 2025Article
- Utility and cost-effectiveness of LiverMultiScan for MASLD diagnosis: a real-world multi-national randomised clinical trial.Communications medicine · 2025Article
- Evaluation of gravity effect on liver and spleen volumes using multiposture MRI.Radiological physics and technology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease in the world, affecting more than 25% of the adult population. NAFLD covers a spectrum including simple steatosis, in which lipid accumulation in hepatocytes is the predominant histological characteristic, and nonalcoholic steatohepatitis (NASH), which is characterized by additional hepatic inflammation with or without fibrosis. Liver biopsy is currently the reference standard to discriminate between hepatic steatosis and steatohepatitis. Since liver biopsy has several disadvantages, noninvasive diagnostic methods with high sensitivity and specificity are desirable for the analysis of NAFLD. Improvements in magnetic resonance imaging (MRI) technology are continuously being implemented in clinical practice, specifically multiparametric MRI methods such as proton density fat-fraction (PDFF), T
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.