Evidence map›Paper›PMID 32821966›Full record

ArticleDer Radiologe2020

[Influence of the "distance to thrombus" in acute middle cerebral artery occlusion : A predictor for the clinical outcome after endovascular treatment].

Ruben Mühl-Benninghaus, Salman Nebilir, Andreas Simgen, Gudrun Wagenpfeil, Michael Kettner, Mathias Fousse, Wolfgang Reith, Umut Yilmaz

Open access · hybridAbstract read
In one paragraph

Article in Der Radiologe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ruben Mühl-BenninghausAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland. ruben.muehl-benninghaus@uks.eu.
Salman NebilirAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland.
Andreas SimgenAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland.
Gudrun WagenpfeilInstitut für Medizinische Biometrie, Epidemiologie und Medizinische Informatik, Universitätsklinikum des Saarlandes, Homburg, Deutschland.
Michael KettnerAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland.
Mathias FousseAbteilung für Neurologie, Universitätsklinikum des Saarlandes, Homburg, Deutschland.
Wolfgang ReithAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland.
Umut YilmazAbteilung für diagnostische und interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, 66424, Homburg, Deutschland.
Universitätsklinikum des Saarlandes · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe therapy strategy of patients with acute stroke of the middle cerebral artery (MCA) is influenced by the location of the occlusion. The purpose of this study was to analyze the clinical outcome in patients with acute ischemic MCA occlusion according to the location of occlusion who underwent endovascular treatment (EVT).

methodsA total of 54 patients (age 73 ± 15 years; 59% female) with acute ACM occlusion treated with EVT were included. In coronary reformatted CT angiography images, the distance to the thrombus (DT), i.e. the distance from the carotid T to the beginning of the thrombus, was measured. Correlations between DT, clinical symptoms, and clinical outcome of patients who underwent EVT were analyzed.

resultsDT correlated with clinical symptoms measured by the National Institutes of Health Stroke Scale (NIHSS; p = 0.017; R = -0.324) at baseline. DT also correlated with the modified Rankin scale after 90 days (90-day mRS; p = 0.014; R = -0.333). DT was a predictor for a good clinical outcome (mRS after 90 days) after EVT; odds ratio 1.113 (P = 0.02; 95% confidence interval [CI] 1.017-1.219). A DT >10 mm correlated significantly (p = 0.036) with a good clinical outcome (90-day mRS ≤2).

conclusionDT correlates with the clinical symptoms of patients with acute MCA occlusion. In addition, DT is an independent predictor of the clinical outcome of patients suffering from acute stroke due to MCA occlusion.

Indexed as

Endovascular ProceduresInfarction, Middle Cerebral ArteryStrokeThrombosisCerebral AngiographyFemaleHumansMaleRetrospective StudiesThrombolytic TherapyTreatment OutcomeCT angiographyIntravenous thrombolysisMechanical thrombectomyStrokeVascular occlusion

Identifiers

PMID32821966
PMCPMC7716895
OpenAlexW3080528402

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.