ReviewLangenbeck's archives of surgery2021
Quantification of fluorescence angiography: Toward a reliable intraoperative assessment of tissue perfusion - A narrative review.
Review in Langenbeck's archives of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Current applications of indocyanine green fluorescence angiography in trauma patients and its potential impact: a systematic review.BMJ open · 2025Pooled it
- Application of fluorescence-guided surgery in the acute care setting: a systematic literature review.Langenbeck's archives of surgery · 2023Pooled it
- Indocyanine green fluorescence imaging for evaluating blood flow in the reconstructed conduit after esophageal cancer surgery.Surgery today · 2022Pooled it
- Indocyanine green fluorescence angiography prevents anastomotic leakage in rectal cancer surgery: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2021Pooled it
- Quantitative assessment of gastric tube perfusion during Ivor Lewis esophagectomy using indocyanine-green: results from the prospective interventional trial SPY Q-ICG PAS study.Surgical endoscopy · 2026Trial
- Fluorescence quantitative assessment of blood perfusion in the gastric conduit to reduce anastomotic leakage after esophagectomy: a randomized controlled trial.Surgical endoscopy · 2025Trial
- Intraoperative spectral imaging versus ICG fluorescence for gastric conduit viability in esophagectomy.Surgical endoscopy · 2026Article
- Intraoperative Multimodal Bowel Perfusion Quantification Combining Hyperspectral Imaging and Indocyanine Green.Diagnostics (Basel, Switzerland) · 2026Article
- Maximal Systolic Acceleration and Near-Infrared Fluorescence Imaging With Indocyanine Green as Predictors for Successful Lower Extremity Revascularization.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2026Article
- Cross-software comparison shows strong agreement for quantitative indocyanine green fluorescence angiography in reconstructive surgery.Frontiers in surgery · 2026Article
- The Role of Quantitative Indocyanine Green Angiography with Relative Perfusion Ratio in the Assessment of Gastric Conduit Perfusion in Oesophagectomy: A Retrospective Study.Journal of clinical medicine · 2025Article
- Impact of indocyanine green fluorescence angiography on esophagogastric anastomotic leakage after Ivor Lewis esophagectomy.Langenbeck's archives of surgery · 2025Article
- Continuous assessment of tissue perfusion using quantitative indocyanine green fluorescence imaging during controlled hypo- and reperfusion.Surgical endoscopy · 2025Article
- A Potential Pitfall in the Interpretation of Microscope-Integrated Fluorescence Angiography: The Center-Periphery Effect.Medical sciences (Basel, Switzerland) · 2025Article
- Intraoperative assessment of myocardial perfusion using near-infrared fluorescence and indocyanine green: A literature review.JTCVS techniques · 2025Article
- A Green Lantern for the Surgeon: A Review on the Use of Indocyanine Green (ICG) in Minimally Invasive Surgery.Journal of clinical medicine · 2024Review
- Clinical and computational development of a patient-calibrated ICGFA bowel transection recommender.Surgical endoscopy · 2024Article
- A feasibility study assessing quantitative indocyanine green angiographic predictors of reconstructive complications following nipple-sparing mastectomy.JPRAS open · 2024Article
- Quantification of fluorescence angiography for visceral perfusion assessment: measuring agreement between two software algorithms.Surgical endoscopy · 2024Article
- Quantification of indocyanine green near-infrared fluorescence bowel perfusion assessment in colorectal surgery.Surgical endoscopy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate intraoperative assessments of tissue perfusion are essential in all forms of surgery. As traditional methods of perfusion assessments are not available during minimally invasive surgery, novel methods are required. Here, fluorescence angiography with indocyanine green has shown promising results. However, to secure objective and reproducible assessments, quantification of the fluorescent signal is essential (Q-ICG). This narrative review aims to provide an overview of the current status and applicability of Q-ICG for intraoperative perfusion assessment.
resultsBoth commercial and custom Q-ICG software solutions are available for intraoperative use; however, most studies on Q-ICG have performed post-operative analyses. Q-ICG can be divided into inflow parameters (ttp, t0, slope, and T
conclusionIntraoperative Q-ICG is clinically available; however, only feasibility studies have been performed, rendering an excellent usability score. Q-ICG in a post-operative setting could detect changes in perfusion following a range of interventions and reflect clinical endpoints, but only if based on inflow parameters. Thus, future studies should include the methodology outlined in this review, emphasizing the use of inflow parameters (slope or T
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.