Evidence map›Paper›PMID 32821881›Full record

ArticleFASEB bioAdvances2020

Uterine infusion of bacteria alters the transcriptome of bovine oocytes.

Rachel L Piersanti, Jeremy Block, Zhengxin Ma, KwangCheol C Jeong, José E P Santos, Fahong Yu, I Martin Sheldon, John J Bromfield

Open access · goldAbstract read
In one paragraph

Article in FASEB bioAdvances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rachel L PiersantiDepartment of Animal Sciences University of Florida Gainesville FL USA.
Jeremy BlockDepartment of Animal Sciences University of Florida Gainesville FL USA.
Zhengxin MaDepartment of Animal Sciences University of Florida Gainesville FL USA.
KwangCheol C JeongDepartment of Animal Sciences University of Florida Gainesville FL USA.
José E P SantosDepartment of Animal Sciences University of Florida Gainesville FL USA.
Fahong YuInterdisciplinary Center for Biotechnology Research University of Florida Gainesville FL USA.
I Martin SheldonInstitute of Life Science Swansea University Medical School Swansea UK.
John J BromfieldDepartment of Animal Sciences University of Florida Gainesville FL USA.
University of Florida · USSwansea University · GB

Funding

Uterine infection and infertility: how microbial infection of the reproductive tract causes ovarian dysfunction.R01HD084316 · NICHD · UNIVERSITY OF FLORIDA · PI BROMFIELD, JOHN J · 2016 to 2020
$1.7M
NICHD NIH HHS R01 HD084316
6 · The paper itself

Abstract

Postpartum uterine infection reduces fertility in dairy cattle; however, the mechanisms of uterine infection-mediated infertility are unknown. Paradoxically, infection-induced infertility persists after the resolution of disease. Oocytes are a finite resource, which are present at various stages of development during uterine infection. It is likely that oocyte development is influenced by uterine infection-induced changes to the follicular microenvironment. To better understand the impact of infection on oocyte quality we employed global transcriptomics of oocytes collected from heifers after receiving intrauterine infusion of pathogenic

Indexed as

endometritisgene expressioninfectioninflammation

Identifiers

PMID32821881
PMCPMC7429353
OpenAlexW3037221286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.