Evidence map›Paper›PMID 32821820›Full record

ArticleScience advances2020

Intercellular communication controls agonist-induced calcium oscillations independently of gap junctions in smooth muscle cells.

S E Stasiak, R R Jamieson, J Bouffard, E J Cram, H Parameswaran

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Stem cells, cell therapies, and bioengineering in lung biology and diseases 2023.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

S E StasiakDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0003-2260-0771
R R JamiesonDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0003-1729-2647
J BouffardDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.
E J CramDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-8129-1326
H ParameswaranDepartment of Bioengineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-5324-5517
Northeastern University · US

Funding

In vivo analysis of mechanotransductionR01GM110268 · NIGMS · NORTHEASTERN UNIVERSITY · PI CRAM, ERIN JEAN · 2014 to 2023
$2.8M
Extracellular determinants of airway smooth muscle force: A new paradigm for sustR00HL122513 · NHLBI · NORTHEASTERN UNIVERSITY · PI PARAMESWARAN, HARIKRISHNAN · 2017 to 2019
$747k
Advanced Image-Based Approach to Assess How Fibrillar Collagen Modulates Airway ReactivityR21HL129468 · NHLBI · NORTHEASTERN UNIVERSITY · PI PARAMESWARAN, HARIKRISHNAN · 2016 to 2017
$443k
Extracellular determinants of airway smooth muscle force: A new paradigm for sustK99HL122513 · NHLBI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI PARAMESWARAN, HARIKRISHNAN · 2014 to 2015
$227k
NHLBI NIH HHS K99 HL122513NHLBI NIH HHS R00 HL122513NHLBI NIH HHS R21 HL129468NIGMS NIH HHS R01 GM110268
6 · The paper itself

Abstract

In this study, we report the existence of a communication system among human smooth muscle cells that uses mechanical forces to frequency modulate long-range calcium waves. An important consequence of this mechanical signaling is that changes in stiffness of the underlying extracellular matrix can interfere with the frequency modulation of Ca

Identifiers

PMID32821820
PMCPMC7406377
OpenAlexW3046987570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.