Evidence map›Paper›PMID 32821728›Full record

ReviewJournal of lipid and atherosclerosis2020

Select Macrophage Noncoding RNAs of Interest in Cardiovascular Disease.

Zenaida Enchill, Connor Lantz, Edward B Thorp

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of lipid and atherosclerosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 64% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Correlation between Complement C1q A Chain (Iranian journal of public health · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Zenaida EnchillDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID https://orcid.org/0000-0003-3431-1379
Connor LantzDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID https://orcid.org/0000-0003-3317-6486
Edward B ThorpDepartment of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID https://orcid.org/0000-0003-1387-7058
Northwestern University · US

Funding

Efferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic HeartR01HL122309 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI THORP, EDWARD BENJAMIN · 2014 to 2024
$5.0M
NHLBI NIH HHS R01 HL122309
6 · The paper itself

Abstract

Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Aspects of disease severity that are associated with heightened inflammation, such as during atherosclerosis or after myocardial infarction, are correlated with macrophage activation and macrophage polarization of the transcriptome and secretome. In this setting, non-coding RNAs (ncRNAs) may be as abundant as protein-coding genes and are increasingly recognized as significant modulators of macrophage gene expression and cytokine secretion, although the functions of most ncRNAs-and in particular, long non-coding RNAs-remain unknown. Herein, we discuss a subset of specific ncRNAs of interest in macrophages in atherosclerosis and during myocardial inflammation.

Indexed as

Cardiovascular diseasesLncRNAMacrophages

Identifiers

PMID32821728
PMCPMC7379065
OpenAlexW3002739779

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.