Evidence map›Paper›PMID 32821720›Full record

ReviewJournal of lipid and atherosclerosis2020

Sphingolipid Mediators of Myocardial Pathology.

Anna Kovilakath, L Ashley Cowart

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of lipid and atherosclerosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Alterations in Cardiac Metabolism byACS infectious diseases · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Mechanisms and prognostic impact of myocardial ischaemia in hypertrophic cardiomyopathy.The international journal of cardiovascular imaging · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Neutral sphingomyelinase-2 and cardiometabolic diseases.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Review
  18. Article
  19. Sphingolipids in the Heart: From Cradle to Grave.Frontiers in endocrinology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anna KovilakathDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-0735-9131
L Ashley CowartDepartment of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.ORCID https://orcid.org/0000-0002-5312-5232
Virginia Commonwealth University · US

Funding

Sptlc3-derived sphingolipids in cardiomyocyte death in ischemiaF31HL156529 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI KOVILAKATH, ANNA PHILIP · 2021 to 2023
$119k
NHLBI NIH HHS F31 HL156529
6 · The paper itself

Abstract

Cardiomyopathy is the leading cause of mortality worldwide. While the causes of cardiomyopathy continue to be elucidated, current evidence suggests that aberrant bioactive lipid signaling plays a crucial role as a component of cardiac pathophysiology. Sphingolipids have been implicated in the pathophysiology of cardiovascular disease, as they regulate numerous cellular processes that occur in primary and secondary cardiomyopathies. Experimental evidence gathered over the last few decades from both

Indexed as

CardiomyocytesCardiomyopathyCeramidesSphingolipidsSphingosine-1-phosphate receptor

Identifiers

PMID32821720
PMCPMC7379069
OpenAlexW2982026539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.