Evidence map›Paper›PMID 32821526›Full record

ArticleTranslational vision science & technology2020

Is Dietary Vitamin A Associated with Myopia from Adolescence to Young Adulthood?

Fletcher J Ng, David A Mackey, Therese A O'Sullivan, Wendy H Oddy, Seyhan Yazar

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Vitamin A and Its Related Diseases.Food science & nutrition · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. The influence of the environment and lifestyle on myopia.Journal of physiological anthropology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Fletcher J NgDepartment of Genetics and Epidemiology, Lions Eye Institute, Perth, Western Australia, Australia.
David A MackeyDepartment of Genetics and Epidemiology, Lions Eye Institute, Perth, Western Australia, Australia.
Therese A O'SullivanSchool of Medical and Health Science, Edith Cowan University, Perth, Western Australia, Australia.
Wendy H OddyMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Seyhan YazarDepartment of Genetics and Epidemiology, Lions Eye Institute, Perth, Western Australia, Australia.
Lions Eye Institute · AUEdith Cowan University · AUUniversity of Tasmania · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Potential links may exist between vitamin A intake and myopia via various pathways. In this study, we examined the association between dietary vitamin A intake during adolescence and myopia in early adulthood. Methods: We performed a prospective analysis utilizing data collected from participants of the Raine Study Gen2. Dietary vitamin A intake, determined via food frequency questionnaires completed at ages 14, 17, and 20 years, was compared with ophthalmic measurements collected at year 20. Low vitamin A levels were defined as <600 µg/day. Regression models were used to adjust for ocular sun exposure level, educational level, and parental myopia as potential confounders. Results: A total of 642 subjects were analyzed. Although those with adequate vitamin A intakes were less likely to be myopic ( Conclusions: There were no significant associations between total vitamin A intakes during adolescence and year 20 refractive errors after adjustment for confounders. Replication of this finding and further investigations are essential to rule out the suggestion that sufficient vitamin A intake during adolescence is associated with lower risk of myopia in early adulthood. Translational Relevance: Our findings are not definitive that ingesting foods high in vitamin A during childhood and adolescence does not have a role for preventing myopia in early adulthood.

Indexed as

MyopiaVitamin AAdolescentAdultDietEyeHumansProspective StudiesYoung AdultVitamin Amyopianearsightednessvitamin Avitamin A deficiency

Identifiers

PMID32821526
PMCPMC7408804
OpenAlexW3031677973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.