Evidence map›Paper›PMID 32821448›Full record

ArticleMedeniyet medical journal2019

The Impact of Prognostic Nutritional Index on Coronary Flow Reserve in Patients with Inflammatory Bowel Disease.

Zuhal Caliskan, Mustafa Adem Tatlisu, Resul Kahraman, Savas Gokturk, Suleyman Sayar, Osman Kostek, Seref Kul, Omer Faruk Baycan, Fatma Gül Ozcan, Mustafa Caliskan

Abstract read
In one paragraph

Article in Medeniyet medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zuhal CaliskanIstanbul Umraniye Training and Research Hospital, Department of Gastroenterology, Istanbul, Turkey.ORCID 0000-0002-0332-2270
Mustafa Adem TatlisuIstanbul Medeniyet University Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.ORCID 0000-0003-1058-7194
Resul KahramanIstanbul Umraniye Training and Research Hospital, Department of Gastroenterology, Istanbul, Turkey.ORCID 0000-0001-5534-0860
Savas GokturkBaskent University Faculty of Medicine, Department of Gastroenterology, Konya, Turkey.ORCID 0000-0001-9402-940X
Suleyman SayarIstanbul Umraniye Training and Research Hospital, Department of Gastroenterology, Istanbul, Turkey.ORCID 0000-0002-1763-9404
Osman KostekBaskent University Faculty of Medicine, Department of Gastroenterology, Konya, Turkey.ORCID 0000-0002-1901-5603
Seref KulIstanbul Medeniyet University Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.ORCID 0000-0001-8094-7402
Omer Faruk BaycanIstanbul Medeniyet University Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.ORCID 0000-0003-3616-2004
Fatma Gül OzcanIstanbul Medeniyet University Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.ORCID 0000-0003-0682-5065
Mustafa CaliskanIstanbul Medeniyet University Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.ORCID 0000-0001-7417-4001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe recurring inflammation of mucosal layer of intestines is known as inflammatory bowel disease (IBD), which can be accompanied by nutritional deficiencies. The association between inflammation and coronary artery disease has been established. Coronary flow reserve (CFR), which is an established method to evaluate combined microvascular and epicardial flow of coronary arteries, can be assessed by using transthoracic echocardiography. The aim of this study was to evaluate the association of Prognostic Nutritional Index (PNI) with CFR in IBD patients.

methodThis prospective study included 101 patients with IBD. These patients were compared to control group (n=32). PNI was calculated by using serum albumin level and lymphocyte count. CFR was assessed by using Doppler echocardiography.

resultsMultivariate regression analysis indicated that the presence of IBD, age (>40 years) and decreased PNI (<53.8) independently predict impairment of CFR. The area under the curve (AUC) was 75.1% (95% CI:0.664-0.838), and PNI levels were significant predictor of low CFR (p<0.001).

conclusionThis study showed that PNI, which is calculated using the serum level of albumin and lymphocyte count, is a strong predictor of decreased CFR in IBD patients in remission. Our findings support previous studies showing the relationship between PNI and coronary artery disease. This immunonutritional index has only two components and is easy to calculate, and inexpensive.

Indexed as

Coronary flow reserveinflammatory bowel diseaseprognostic nutritional index

Identifiers

PMID32821448
PMCPMC7433735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.