ArticleBone research2020
Inhibition of Axin1 in osteoblast precursor cells leads to defects in postnatal bone growth through suppressing osteoclast formation.
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Article in Bone research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- PSVRP: a pig structural variant reference panel for complex trait genomics and precision breeding.BMC genomics · 2025Article
- Genetics, epidemiology and management of clubfoot and related disorders.Genes & diseases · 2025Review
- PTHrP buffers Wnt/β-catenin activity through a PKC-ζ involved negative feedback loop to maintain articular cartilage homeostasis and attenuate osteoarthritis.Journal of orthopaedic translation · 2025Article
- Skeletal stem cells, a new direction for the treatment of bone and joint diseases.World journal of orthopedics · 2025Review
- Axin formation inhibitor 1 aggravates hepatic ischemia‒reperfusion injury by promoting the ubiquitination and degradation of PPARβ.Nature communications · 2025Article
- The role and mechanism of β-catenin-mediated skeletal muscle satellite cells in osteoporotic fractures by Jian-Pi-Bu-Shen formula.Journal of molecular histology · 2024Article
- Cell signaling and transcriptional regulation of osteoblast lineage commitment, differentiation, bone formation, and homeostasis.Cell discovery · 2024Review
- Local Application of Tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing in ovariectomized mice.Journal of orthopaedic surgery and research · 2024Article
- The scaffold protein AXIN1: gene ontology, signal network, and physiological function.Cell communication and signaling : CCS · 2024Review
- Monotropein Protects Mesenchymal Stem Cells from Lipopolysaccharide-Induced Impairments and Promotes Fracture Healing in an Ovariectomized Mouse Model.Calcified tissue international · 2023Article
- AmbientEnvironmental health perspectives · 2023Article
- AXIN1 bi-allelic variants disrupting the C-terminal DIX domain cause craniometadiaphyseal osteosclerosis with hip dysplasia.American journal of human genetics · 2023Article
- Comprehensive analysis on subchondral bone marrow lesions of human osteoarthritis by integrating bulk and single-cell transcriptomes.BMC musculoskeletal disorders · 2023Article
- The Role of the Piezo1 Mechanosensitive Channel in the Musculoskeletal System.International journal of molecular sciences · 2023Review
- GATA4 and estrogen receptor alpha bind at SNPs rs9921222 and rs10794639 to regulate AXIN1 expression in osteoblasts.Human genetics · 2022Article
- A 92 protein inflammation panel performed on sonicate fluid differentiates periprosthetic joint infection from non-infectious causes of arthroplasty failure.Scientific reports · 2022Article
- Drug repositioning of polaprezinc for bone fracture healing.Communications biology · 2022Article
- Effect of Regulator of G Protein Signaling Proteins on Bone.Frontiers in endocrinology · 2022Review
- Roles of mechanosensitive channel Piezo1/2 proteins in skeleton and other tissues.Bone research · 2021Review
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 2 countries.
Bing Shu *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Yongjian Zhao *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Shitian ZhaoLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Haobo PanResearch Center for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
Rong XieDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612 USA.
Dan YiResearch Center for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
Ke LuDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612 USA.ORCID 0000-0002-1641-4748
Junjie YangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Chunchun XueLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Jian HuangDepartment of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612 USA.ORCID 0000-0002-6676-5159
Jing WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Dongfeng ZhaoLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Guozhi XiaoSchool of Medicine, Southern University of Science and Technology, Shenzhen, 518055 China.
Yongjun WangLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 725 WanPing South Road, Shanghai, 200032 China.
Di ChenResearch Center for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
Ministry of Education of the People's Republic of China · CNChinese Academy of Sciences · CNRush University Medical Center · USSouthern University of Science and Technology · CN
Funding
The Role of MicroRNA in Osteoarthritis: Alzheimer's Administrative SupplementR01AR070222 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI HUANG, JIAN, ZHAO, LAN · 2017 to 2022
$2.1MChinese Academy of Sciences (CAS) QYZDB-SSW-JSC030Ministry of Education of the People's Republic of China (Ministry of Education of China) IRT1270Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2015RA4002Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2018YFC1704302National Natural Science Foundation of China (National Science Foundation of China) 81603643National Natural Science Foundation of China (National Science Foundation of China) 81672227National Natural Science Foundation of China (National Science Foundation of China) 81673991National Natural Science Foundation of China (National Science Foundation of China) 81973876National Natural Science Foundation of China (National Science Foundation of China) 81991513NIAMS NIH HHS R01 AR070222Shanghai Municipal Health Bureau (Shanghai Municipal Public Health Bureau) ZY (2018-2020)-CCCX-3003
Abstract
Axin1 is a negative regulator of β-catenin signaling and its role in osteoblast precursor cells remains undefined. In the present studies, we determined changes in postnatal bone growth by deletion of
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.