Evidence map›Paper›PMID 32821439›Full record

ArticleCell death discovery2020

Fecal microbiota transplantation from patients with autoimmune encephalitis modulates Th17 response and relevant behaviors in mice.

Hao Chen, Zhaoyu Chen, Liping Shen, Xiuhua Wu, Xueying Ma, Dengna Lin, Man Zhang, Xiaomeng Ma, Yingying Liu, Zhanhang Wang and 8 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06584045 (An Open Label Clinical Trial to Evaluate the Efficacy and Safety of Calculus Bovis Sativus), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06584045 narecruitingnot on this mapstarted 2024, after this paper: background citation

An Open Label Clinical Trial to Evaluate the Efficacy and Safety of Calculus Bovis Sativus (CBS) for Adult Encephalitis

TypeinterventionalSponsorTongji HospitalRan2024 to 2029Enrolled250ConditionsEncephalitis, Encephalitis, Viral, Autoimmune Encephalitis Caused by N-Methyl D-Aspartate Receptor Antibody, Autoimmune EncephalitisArmsCalculus bovis sativus (CBS)
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Deciphering autoimmune encephalitis: Immune mechanisms, therapeutic paradigms, and global research trends.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Efficacy of Heshouwu () on gut mircobiota in mice with autoimmune encephalomyelitis.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2023
    Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Role of Interleukin-17 in Acute Pancreatitis.Frontiers in immunology · 2021
    Review
  17. Observational
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Hao Chen *Department of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Zhaoyu Chen *Department of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Liping Shen *Department of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Xiuhua WuDepartment of Psychiatry, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Xueying MaDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Dengna LinDepartment of Infectious Diseases, Third Affiliated Hospital, 510630 Guangzhou, China.
Man ZhangSchool of Environmental and Biological Sciences, The State University of New Jersey, New Brunswick, NJ USA.
Xiaomeng MaDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Yingying LiuDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Zhanhang WangDepartment of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China.
Yuefeng ZhangDepartment of Neurology, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Zuying KuangDepartment of Neurology, Guangdong 999 Brain Hospital, Guangzhou, China.
Zhiwei LuDepartment of Neurology, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, China.
Xuefei LiYanke Biotechnology Co., Guangzhou, China.
Lili MaDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Xiuli LinDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Lei SiDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Xiaohong ChenDepartment of Neurology and Multiple Sclerosis Research Center, The Third Affiliated Hospital, Sun Yat-Sen University, 600 Tianhe Road, 510630 Guangzhou, Guangdong Province China.
Third Affiliated Hospital of Sun Yat-sen University · CNSun Yat-sen University · CNGuangdong 999 Brain Hospital · CNGuangzhou Medical University · CNRutgers, The State University of New Jersey · USThird Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The significance of the microbiota-gut-brain axis has been increasingly recognized as a major modulator of autoimmunity. Here, we aim to characterize the gut microbiota of a large cohort of treatment-naïve anti-

Indexed as

DiseasesImmunologyMicrobiology

Identifiers

PMID32821439
PMCPMC7419566
OpenAlexW3048460873

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.