Evidence map›Paper›PMID 32821284›Full record

Trial reportCardiovascular therapeutics2020

Combined Aerobic and Resistance Exercises Evokes Longer Reductions on Ambulatory Blood Pressure in Resistant Hypertension: A Randomized Crossover Trial.

Nayara Fraccari Pires, Helio José Coelho-Júnior, Bruno Bavaresco Gambassi, Ana Paula Cabral de Faria, Alessandra Mileni Versuti Ritter, Catarina de Andrade Barboza, Silvia Elaine Ferreira-Melo, Bruno Rodrigues, Heitor Moreno Júnior

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Cardiovascular therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Trends in exercise for hypertension: a bibliometric analysis.Frontiers in cardiovascular medicine · 2023
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nayara Fraccari PiresLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Helio José Coelho-JúniorLaboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.ORCID https://orcid.org/0000-0001-7482-9514
Bruno Bavaresco GambassiLaboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.ORCID https://orcid.org/0000-0003-3852-0602
Ana Paula Cabral de FariaLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.ORCID https://orcid.org/0000-0001-8585-7238
Alessandra Mileni Versuti RitterLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Catarina de Andrade BarbozaLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Silvia Elaine Ferreira-MeloLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Bruno RodriguesLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.ORCID https://orcid.org/0000-0003-4246-4703
Heitor Moreno JúniorLaboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.ORCID https://orcid.org/0000-0001-6330-697X
Universidade Estadual de Campinas (UNICAMP) · BRUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe present study compared the acute effects of aerobic (AER), resistance (RES), and combined (COM) exercises on blood pressure (BP) levels in people with resistant hypertension (RH) and nonresistant hypertension (NON-RH).

methodsTwenty patients (10 RH and 10 NON-RH) were recruited and randomly performed three exercise sessions and a control session. Ambulatory BP was monitored over 24 hours after each experimental session.

resultsSignificant reductions on ambulatory BP were found in people with RH after AER, RES, and COM sessions. Notably, ambulatory BP was reduced during awake-time and night-time periods after COM. On the other hand, the effects of AER were more prominent during awake periods, while RES caused greater reductions during the night-time period. In NON-RH, only RES acutely reduced systolic BP, while diastolic BP was reduced after all exercise sessions. However, the longest postexercise ambulatory hypotension was observed after AER (~11 h) in comparison to RES (~8 h) and COM (~4 h) exercises.

conclusionFindings of the present study indicate that AER, RES, and COM exercises elicit systolic and diastolic postexercise ambulatory hypotension in RH patients. Notably, longer hypotension periods were observed after COM exercise. In addition, NON-RH and RH people showed different changes on BP after exercise sessions, suggesting that postexercise hypotension is influenced by the pathophysiological bases of hypertension.

Indexed as

Blood PressureResistance TrainingAdultAgedAntihypertensive AgentsBlood Pressure Monitoring, AmbulatoryBrazilCross-Over StudiesDrug ResistanceFemaleHumansHypertensionMaleMiddle AgedTime FactorsTreatment OutcomeAntihypertensive Agents

Identifiers

PMID32821284
PMCPMC7416229
OpenAlexW3046465600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.