Evidence map›Paper›PMID 32821078›Full record

Trial reportWorld journal of gastroenterology2020

Epigastric pain syndrome: What can traditional Chinese medicine do? A randomized controlled trial of Biling Weitong Granules.

Yan-Dong Wen, Fang Lu, Ying-Pan Zhao, Ping Wang, Qian Yang, Jun-Xiang Li, Hui-Zhen Li, Li-Li Chi, Zheng-Hua Zhou, Yan-Ping Tang and 3 more

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in World journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Yan-Dong WenDepartment of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Fang LuInstitution of Clinical Pharmacology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Ying-Pan ZhaoDepartment of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Ping WangDepartment of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Qian YangDepartment of Gastroenterology, Hebei Provincial Hospital of Chinese Medicine, Shijiazhuang 050011, Hebei Province, China.
Jun-Xiang LiDepartment of Gastroenterology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
Hui-Zhen LiSecond Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China.
Li-Li ChiDepartment of Gastroenterology, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong Province, China.
Zheng-Hua ZhouDepartment of Gastroenterology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China.
Yan-Ping TangDepartment of Gastroenterology, Tianjin Nankai Hospital, Tianjin 300100, China.
Jin-Kang XuDepartment of Gastroenterology, The Kunshan Hospital Affiliated to Nanjing University of Chinese Medicine, Kunshan 215300, Jiangsu Province, China.
Yang ZhaoInstitution of Clinical Pharmacology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China.
Xu-Dong TangDepartment of Gastroenterology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing 100091, China. txdly@sina.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNXiyuan Hospital · CNBeijing University of Chinese Medicine · CNTianjin Nankai Hospital · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent research suggests that although prokinetic agents, acid suppressors, and radical treatment for

aimTo evaluate the clinical efficacy and safety of BLWTG in treating EPS in patients with FD.

methodsIn this multicenter, stratified, randomized, double-blind, placebo-controlled, parallel group clinical trial, eligible patients were randomized into the BLWTG and placebo groups who were treated for 6 wk. Efficacy indicators including the severity and frequency of EPS and the time to pain resolution and safety indicators including adverse events were observed and compared.

resultsThe baseline demographic data and clinical characteristics, such as epigastric pain symptoms, pain intensity, and frequency of attacks, were matched between the two groups before randomization. After 6 wk of treatment and after the center effect was eliminated, the epigastric pain was significantly improved in 28.33% and 85.59% of the patients in the placebo and BLWTG groups, respectively (

conclusionCompared with placebo, BLWTG markedly improved EPS in FD patients without causing serious adverse reactions.

Indexed as

DyspepsiaHelicobacter InfectionsHelicobacter pyloriDouble-Blind MethodHumansMedicine, Chinese TraditionalQuality of LifeTreatment OutcomeBiling Weitong GranulesCompound formulaEpigastric pain syndromeFunctional dyspepsiaRandomized controlled trialTraditional Chinese medicine

Identifiers

PMID32821078
PMCPMC7403800
OpenAlexW3045816171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.