Evidence map›Paper›PMID 32820566›Full record

ArticleMagnetic resonance in medicine2021

Dynamic volumetric hyperpolarized

Kofi Deh, Kristin L Granlund, Roozbeh Eskandari, Nathaniel Kim, Arsen Mamakhanyan, Kayvan R Keshari

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026
    Article
  2. HyperpolarizedMagnetic resonance in medicine · 2024
    Article
  3. Denoising of hyperpolarizedMagnetic resonance in medicine · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kofi DehDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-3919-2543
Kristin L GranlundDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.ORCID 0000-0002-2105-4716
Roozbeh EskandariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Nathaniel KimDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Arsen MamakhanyanDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Kayvan R KeshariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Development of large-field-of-view hyperpolarized MRIR01CA237466 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI CUNNINGHAM, CHARLES H., HRICAK, HEDVIG · 2020 to 2024
$3.4M
Reproducibility of Hyperpolarized Pyruvate Metabolic Imaging in Prostate CancerR01CA195476 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2016 to 2018
$822k
Human Tissue Culture Bioreactor and Hyperpolarized MR for Biomarker DiscoveryR00EB014328 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI KESHARI, KAYVAN R · 2013 to 2015
$735k
GE Diamond DNP PolarizerS10OD016422 · OD · SLOAN-KETTERING INST CAN RESEARCH · PI HRICAK, HEDVIG, KESHARI, KAYVAN R · 2014 to 2014
$600k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA195476NCI NIH HHS R01 CA237466NIBIB NIH HHS R00 EB014328NIH HHS S10 OD016422
6 · The paper itself

Abstract

purposeTo generate dynamic, volumetric maps of hyperpolarized [1-

methodsMaps of chemical species were generated with iterative least squares (IDEAL) reconstruction from multiecho echo-planar imaging (EPI) of phantoms of thermally polarized

resultsImproved separation of chemical species by IDEAL, evaluated by the amount of residual signal measured for chemicals not present in the phantoms, was observed as the number of EPI shots was increased from one to four. Dynamic three-dimensional metabolite maps of [1-

conclusionsIDEAL decomposition of multishot multiecho 13C EPI images is a simple, yet robust method for generating high-quality dynamic volumetric maps of hyperpolarized [1-

Indexed as

Echo-Planar ImagingPyruvic AcidAnimalsCarbon IsotopesLactic AcidLeast-Squares AnalysisMagnetic Resonance ImagingMicePhantoms, ImagingCarbon IsotopesLactic AcidPyruvic Acidhyperpolarized 13CIDEALmetabolic imagingmultiecho echo-planar imaging

Identifiers

PMID32820566
PMCPMC8261862

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.