ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Prototype device for endoventricular beta-emitting radiotracer detection and molecularly-guided intervention.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Advanced Robotics for the Next-Generation of Cardiac Interventions.Micromachines · 2025Review
- Radiotracers to Address Unmet Clinical Needs in Cardiovascular Imaging, Part 1: Technical Considerations and Perfusion and Neuronal Imaging.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Review
- Fantastic voyage: Catheter-based quantification of tracer distribution on a miniature scale.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Nuclear Cardiac Imaging in the Interventional Suite.Current cardiology reports · 2022Review
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWe have set out to develop a catheter-based theranostic system that: (a) identifies diseased and at-risk myocardium via endocardial detection of systemically delivered β-emitting radiotracers and (b) utilizes molecular signals to guide delivery of therapeutics to appropriate tissue via direct intramyocardial injection.
methodsOur prototype device consists of a miniature β-radiation detector contained within the tip of a flexible intravascular catheter. The catheter can be adapted to incorporate an injection port and retractable needle for therapeutic delivery. The performance of the β-detection catheter was assessed in vitro with various β-emitting radionuclides and ex vivo in hearts of pigs following systemic injection of
resultsThe β-detection catheter demonstrated sensitive in vitro detection of β-radiation from
conclusionThe prototype β-detection catheter demonstrates sensitive and selective detection of β
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.