Evidence map›Paper›PMID 32820420›Full record

ArticleJournal of general internal medicine2021

Primary Care Prognostic (PCP) Index of 11-Year Mortality Risk: Development and Validation of a Brief Prognostic Tool.

Grace Shu Hui Chiang, Ma Shwe Zin Nyunt, Qi Gao, Shiou Liang Wee, Keng Bee Yap, Boon Yeow Tan, Tze Pin Ng

Open access · bronzeAbstract read
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Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Grace Shu Hui ChiangDepartment of Medicine, St Luke's Hospital, Singapore, Singapore.ORCID http://orcid.org/0000-0001-8012-9709
Ma Shwe Zin NyuntSingapore Eye Research Institute, Singapore, Singapore.
Qi GaoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Shiou Liang WeeGeriatric Education and Research Institute, Singapore, Singapore.
Keng Bee YapDepartment of Geriatric Medicine, Ng Teng Fong Hospital, Singapore, Singapore.
Boon Yeow TanDepartment of Medicine, St Luke's Hospital, Singapore, Singapore.
Tze Pin NgGeriatric Education and Research Institute, Singapore, Singapore. pcmngtp@nus.edu.sg.
National University of Singapore · SGGeriatric Education and Research Institute · SGNg Teng Fong General Hospital · SGSingapore Eye Research Institute · SGSt Luke's Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare providers use a life expectancy of at least 5 to 10 years in shared clinical decision-making with older adults about cancer screening, major surgeries, and disease prevention interventions. At present, few prognostic indexes predict long-term mortality beyond 10 years or are suited for use in primary care settings.

objectiveWe developed and validated an 8-item multidimensional index predicting 11-year mortality for use in primary care. DESIGN, SETTING, AND

participantsUsing data from the Singapore Longitudinal Ageing Studies (SLAS), we developed a Primary Care Prognostic (PCP) Index for predicting 11-year mortality risk in a development cohort (n = 1550) and validated it in a geographically different cohort (n = 928). MAIN MEASURES: The PCP Index was derived from eight indicators (body mass loss, weakness, slow gait, comorbidity, polypharmacy, IADL/BADL dependency, low albumin, low total cholesterol, out of 25 candidate indicators) using stepwise Cox proportional hazard models. KEY

resultsIn the developmental cohort, the mortality hazard ratio increased by 53% per PCP point score increase, independent of age and sex. Across risk categories, absolute risks of mortality increased from 5% (score 0) to 67.9% (scores 7-9), with area under curve (AUC = 0.77 (95% CI 0.73-0.80)). The PCP Index also predicted mortality in the validation cohort, with AUC = 0.70 (95% CI 0.64-0.75).

conclusionsThe PCP Index using simple clinical assessments and point scoring is a potentially useful prognostic tool for predicting long-term mortality and is well suited for risk stratification and shared clinical decision-making with older adults in primary care.

Indexed as

FrailtyAgedComorbidityHumansPrimary Health CarePrognosisSingaporefrailtymalnutritionmortalityolder adultsprognosis

Identifiers

PMID32820420
PMCPMC7858716
OpenAlexW3081322139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.