Evidence map›Paper›PMID 32820376›Full record

SynthesisActa neurochirurgica2020

Treatment of posttraumatic syringomyelia: evidence from a systematic review.

Andrea Kleindienst, Francisco Marin Laut, Verena Roeckelein, Michael Buchfelder, Frank Dodoo-Schittko

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Acta neurochirurgica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. A novel Minimally-Invasive technique for Non-Traumatic postoperative adhesive Syringomyelia.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  11. Diagnosis and treatment of Chiari malformation and syringomyelia in adults: international consensus document.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Andrea KleindienstDepartment of Neurosurgery, Friedrich-Alexander-University Erlangen-Nurnberg, Erlangen, Germany. andrea.kleindienst@uk-erlangen.de.ORCID 0000-0003-4758-0324
Francisco Marin LautDepartment of Neurosurgery, University Hospital Puerta de Mar, Cadiz, Spain.
Verena RoeckeleinDepartment of Spine Surgery, Krankenhaus Rummelsberg, Schwarzenbruck, Germany.
Michael BuchfelderDepartment of Spine Surgery, Krankenhaus Rummelsberg, Schwarzenbruck, Germany.
Frank Dodoo-SchittkoInstitute of Social Medicine and Health Systems Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEHospital Universitario Puerta del Mar · ESOtto-von-Guericke-Universität Magdeburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFollowing spinal cord injury (SCI), the routine use of magnetic resonance imaging (MRI) resulted in an incremental diagnosis of posttraumatic syringomyelia (PTS). However, facing four decades of preferred surgical treatment of PTS, no clear consensus on the recommended treatment exists. We review the literature on PTS regarding therapeutic strategies, outcomes, and complications.

methodsWe performed a systematic bibliographic search on ("spinal cord injuries" [Mesh] AND "syringomyelia" [Mesh]). English language literature published between 1980 and 2020 was gathered, and case reports and articles examining syrinx due to other causes were excluded. The type of study, interval injury to symptoms, severity and level of injury, therapeutic procedure, duration of follow-up, complications, and outcome were recorded.

resultsForty-three observational studies including 1803 individuals met the eligibility criteria. The time interval from SCI to the diagnosis of PTS varied between 42 and 264 months. Eighty-nine percent of patients were treated surgically (n = 1605) with a complication rate of 26%. Symptoms improved in 43% of patients postoperatively and in 2% treated conservatively. Stable disease was documented in 50% of patients postoperatively and in 88% treated conservatively. The percentage of deterioration was similar (surgery 16%, 0.8% dead; conservative 10%). Detailed analysis of surgical outcome with regard to symptoms revealed that pain, motor, and sensory function could be improved in 43 to 55% of patients while motor function deteriorated in around 25%. The preferred methods of surgery were arachnoid lysis (48%) and syrinx drainage (31%).

conclusionEven diagnosing PTS early in its evolution with MRI, to date, no satisfactory standard treatment exists, and the present literature review shows similar outcomes, regardless of the treatment modality. Therefore, PTS remains a neurosurgical challenge. Additional research is required using appropriate study designs for improving treatment options.

Indexed as

AdultDecompression, SurgicalDrainageFemaleHumansMaleMiddle AgedPostoperative ComplicationsReoperationSensationSpinal Cord InjuriesSyringomyeliaEtiologyHydromyeliaSpinal cord injurySyringomyeliaTraumaTreatment

Identifiers

PMID32820376
PMCPMC7496040
OpenAlexW3060726411

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.