ArticleScientific reports2020
Performance demonstration of a hybrid Compton camera with an active pinhole for wide-band X-ray and gamma-ray imaging.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Multiplexed imaging of radionuclides.Nature biomedical engineering · 2025Review
- Monte Carlo simulation study to explore optimum conditions for Astatine-211 SPECT.Radiological physics and technology · 2023Article
- A Wide Energy Range and 4π-View Gamma Camera with Interspaced Position-Sensitive Scintillator Array and Embedded Heavy Metal Bars.Sensors (Basel, Switzerland) · 2023Article
- Hybrid PET/Compton-camera imaging: an imager for the next generation.European physical journal plus · 2023Review
- High-sensitivity cardiac SPECT system design with collimator-less interspaced mosaic-patterned scintillators.Frontiers in medicine · 2023Article
- Development and Applications of Compton Camera-A Review.Sensors (Basel, Switzerland) · 2022Review
- Compton imaging for medical applications.Radiological physics and technology · 2022Review
- Simultaneous multi-nuclide imaging via double-photon coincidence method with parallel hole collimators.Scientific reports · 2021Article
- KSNM 60 years: International Collaboration with Asian Nuclear Medicine Community.Nuclear medicine and molecular imaging · 2021Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
X-ray and gamma-ray imaging are technologies with several applications in nuclear medicine, homeland security, and high-energy astrophysics. However, it is generally difficult to realize simultaneous wide-band imaging ranging from a few tens of keV to MeV because different interactions between photons and the detector material occur, depending on the photon energies. For instance, photoabsorption occurs below 100 keV, whereas Compton scattering dominates above a few hundreds of keV. Moreover, radioactive sources generally emit both X-ray and gamma-ray photons. In this study, we develop a "hybrid" Compton camera that can simultaneously achieve X-ray and gamma-ray imaging by combining features of "Compton" and "pinhole" cameras in a single detector system. Similar to conventional Compton cameras, the detector consists of two layers of scintillator arrays with the forward layer acting as a scatterer for high-energy photons (> 200 keV) and an active pinhole for low-energy photons (< 200 keV). The experimental results on the performance of the hybrid camera were consistent with those from the Geant4 simulation. We simultaneously imaged [Formula: see text]Am (60 keV) and [Formula: see text]Cs (662 keV) in the same field of view, achieving an angular resolution of 10[Formula: see text] (FWHM) for both sources. In addition, imaging of [Formula: see text]At was conducted for the application in future nuclear medicine, particularly radionuclide therapy. The initial demonstrative images of the [Formula: see text]At phantom were reconstructed using the pinhole mode (using 79 keV) and Compton mode (using 570 keV), exhibiting significant similarities in source-position localization. We also verified that a mouse injected with 1 MBq of [Formula: see text]At can be imaged via pinhole-mode measurement in an hour.
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