Evidence map›Paper›PMID 32819942›Full record

ArticleBMJ open2020

Development of the generic, multidimensional Treatment Expectation Questionnaire (TEX-Q) through systematic literature review, expert surveys and qualitative interviews.

Jannis Alberts, Bernd Löwe, Maja Alicia Glahn, Keith Petrie, Johannes Laferton, Yvonne Nestoriuc, Meike Shedden-Mora

3 registry-linked trialsAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05254704 unknown statusnot on this mapstarted 2022, after this paper: background citation

Validation of the French Version of the TEX-Q Questionnaire to Assess Patient's Expectations Regarding Their Surgery and Their Anesthesia.

TypeobservationalSponsorUniversity Hospital, AngersRan2022 to 2022Enrolled200ConditionsExpectations, Anesthesia, Surgery, Quality of LifeArmsTEX-Q-F before scheduled surgery
NCT06080997 recruitingnot on this mapstarted 2024, after this paper: background citation

Patients' Expectations Before, and Their Experiences After Spinal Surgery, Regarding Pain, Rehabilitation and Quality of Life

TypeobservationalSponsorZealand University HospitalRan2024 to 2026Enrolled300ConditionsExpectations, Surgery, Pain, Quality of Life
NCT07689396 recruitingnot on this mapstarted 2026, after this paper: background citation

Determining the Predictors of Treatment Expectations in Individuals With Myofascial Pain Syndrome: A Cross-Sectional Study

TypeobservationalSponsorKTO Karatay UniversityRan2026 to 2026Enrolled85ConditionsMyofascial Pain Syndromes
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jannis AlbertsPsychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-9680-1528
Bernd LöwePsychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-4220-3378
Maja Alicia GlahnPsychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Keith PetriePsychological Medicine, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-6337-2480
Johannes LafertonClinical Psychology and Psychotherapy, Psychologische Hochschule Berlin, Berlin, Germany.ORCID 0000-0001-5044-5540
Yvonne NestoriucDepartment of Clinical Psychology, Helmut Schmidt University, University of the Federal Armed Forces, Hamburg, Germany.ORCID 0000-0003-2191-0495
Meike Shedden-MoraPsychosomatic Medicine and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany m.shedden-mora@uke.de.ORCID 0000-0003-2023-3824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePatients' expectations-as a central mechanism of placebo and nocebo effects-are an important predictor of health outcomes. However, the lack of a way to assess expectations across different settings restricts progress in understanding the role of expectations and to quantify their importance in medical and psychological treatments. The aim of this study was to develop a theory-based, generic, multidimensional measure assessing patient expectations of medical and psychological treatments.

designThe Treatment Expectation Questionnaire (TEX-Q) was developed based on the integrative model of expectations and a systematic literature review of treatment expectation scales. After creating a comprehensive item pool, the scale was further refined by use of expert ratings and patient interviews.

settingPatients were recruited in primary care at two hospitals in Hamburg, Germany.

participants13 scientific experts participated in the expert survey. 11 patients waiting for psychological or surgical treatments participated in the qualitative interviews.

resultsThe 2×2×2 multidimensional structure of the TEX-Q assesses two expectation constructs (probabilistic vs value-based) across two outcome domains with two valences (direct benefits and adverse events, broader positive and negative impact), plus process and behavioural control expectations. We examined 583 items from 38 scales identified in the systematic review and developed 78 initial items. Content validity was then rated by experts according to item fit and comprehensibility. The best 53 items were further evaluated for comprehensibility, acceptability, phrasing preference and understanding by interviewing patients prior to treatment using the 'think aloud' technique. This resulted in a first 35-item version of the TEX-Q.

conclusionsThe TEX-Q is a generic, multidimensional measure to assess patient expectations of medical and psychological treatments and allows comparison of the impact of multidimensional expectations across different conditions. The final TEX-Q will be available after psychometric validation.

Indexed as

Drugs, GenericMotivationSurveys and QuestionnairesGermanyHumansPsychometricsReproducibility of ResultsDrugs, Genericgeneral medicine (see internal medicine)mental healthpreventive medicinequalitative researchstatistics & research methodstherapeutics

Identifiers

PMID32819942
PMCPMC7440833

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.