SynthesisAJNR. American journal of neuroradiology2020
Lack of Baseline Intracranial Aneurysm Wall Enhancement Predicts Future Stability: A Systematic Review and Meta-Analysis of Longitudinal Studies.
Synthesis in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Does it stable? Intracranial aneurysm wall enhancement might be the warning signals: a meta-analysis of observational studies.Neurosurgical review · 2024Pooled it
- A Systematic Review and Meta-Analysis of the Pathology Underlying Aneurysm Enhancement on Vessel Wall Imaging.International journal of molecular sciences · 2024Pooled it
- Intracranial aneurysm wall enhancement as an indicator of instability: a systematic review and meta-analysis.European journal of neurology · 2021Pooled it
- Achievement and Future Prospectives from Translational Research Targeting Intracranial Aneurysm.Neurologia medico-chirurgica · 2026Review
- Local pressure as a dominant hemodynamic driver of wall enhancement in anterior communicating artery aneurysms: a facet-level computational fluid dynamics and vessel wall imaging analysis.Quantitative imaging in medicine and surgery · 2026Article
- Evaluation of radiogenomics for risk stratification of intracranial aneurysms: a pilot study.Neuroradiology · 2025Article
- Comprehensive morphomechanical and wall enhancement analysis of intracranial aneurysms.European radiology · 2025Article
- Evaluation of Radiogenomics for Risk Stratification of Intracranial Aneurysms: A Pilot Study.Research square · 2025Article
- Challenges in identifying ruptured aneurysms in cases of multiple aneurysms: Utilizing MRI with contrast for surgical planning-A case report.Clinical case reports · 2024Article
- PET imaging of unruptured intracranial aneurysm inflammation (PET-IA) study: a feasibility study protocol.BMJ open · 2024Article
- Advancing vessel wall imaging in intracranial aneurysms: a crucial step towards improved patient management?Acta neurochirurgica · 2023Article
- Focal Aneurysm Wall Enhancement in Vessel Wall Imaging as a Surrogate Marker for Predicting Aneurysm Instability.Stroke (Hoboken, N.J.) · 2023Article
- Wall enhancement as a biomarker of intracranial aneurysm instability: a histo-radiological study.Acta neurochirurgica · 2023Observational
- The role of vessel wall imaging in determining the best treatment approach for coexisting aneurysms and subarachnoid hemorrhage.Acta neurologica Belgica · 2023Article
- Brain Aneurysm Biology: What Can We Learn From Imaging?Stroke (Hoboken, N.J.) · 2022Article
- Topographical Analysis of Aneurysm Wall Enhancement With 3-Dimensional Mapping.Stroke (Hoboken, N.J.) · 2022Article
- Vessel Wall MRI: clinical implementation in cerebrovascular disorders-technical aspects.La Radiologia medica · 2022Article
- High-Resolution Vessel Wall MRI of Endovascularly Treated Intracranial Aneurysms.Tomography (Ann Arbor, Mich.) · 2022Article
- Current Clinical Applications of Intracranial Vessel Wall MR Imaging.Seminars in ultrasound, CT, and MR · 2021Review
- Semiautomated 3D mapping of aneurysmal wall enhancement with 7T-MRI.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe utility of vessel wall MR imaging in identifying unstable intracranial aneurysms has been suggested but remains controversial. PURPOSE: Our aim was to provide further insight into the potential relationship between aneurysm wall enhancement on initial vessel wall imaging and aneurysm instability at follow-up. DATA SOURCES: Our sources were PubMed, Scopus, the Web of Science, and the Cochrane Central Register of Controlled Trials. STUDY SELECTION: We searched for English language studies that reported the presence of vessel wall enhancement of unruptured intracranial aneurysms on baseline vessel wall imaging studies with longitudinal follow-up of aneurysm status. DATA ANALYSIS: Aneurysms were grouped into "stable" and "unstable" groups at follow-up on the basis of growth, symptomatic manifestation, or rupture. The association of each group with aneurysm wall enhancement on initial vessel wall imaging was determined. DATA SYNTHESIS: Three studies constituting 407 aneurysms were included. Aneurysms with wall enhancement were at higher risk of being unstable at follow-up (risk ratio = 3.6; 95% confidence interval, 1.7-7.5). The sensitivity of aneurysm wall enhancement on vessel wall imaging was 74.3% (95% CI, 56.7%-87.5%), specificity was 58.3% (95% CI, 53.1%-63.4%), positive predictive value was 14.4% (95% CI, 11.8%-17.4%), negative predictive value was 96.0% (95% CI, 93.2%-97.7%), and the overall accuracy of the test was 59.7% (95% CI, 54.8%-64.5%). LIMITATIONS: Only 3 studies were identified for inclusion in this analysis. More longitudinal studies of vessel wall imaging and aneurysm progression are needed.
conclusionsThe lack of wall enhancement may be a predictor of aneurysm stability. The utility of vessel wall imaging in detecting unstable aneurysms requires more data.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.