Evidence map›Paper›PMID 32819899›Full record

ArticleAJNR. American journal of neuroradiology2020

Brain Imaging of Patients with COVID-19: Findings at an Academic Institution during the Height of the Outbreak in New York City.

E Lin, J E Lantos, S B Strauss, C D Phillips, T R Campion, B B Navi, N S Parikh, A E Merkler, S Mir, C Zhang and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 11 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 11 syntheses or guidelines pooled it, 104 citations in OpenAlex.

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  7. COVID-19 associated cranial nerve neuropathy: A systematic review.Bosnian journal of basic medical sciences · 2022
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  19. Effects of COVID-19 on cognition and brain health.Trends in cognitive sciences · 2023
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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

E LinFrom the Department of Radiology (E.L., J.E.L., S.B.S., C.D.P., A.G.) eal9007@med.cornell.edu.ORCID 0000-0003-1860-4059
J E LantosFrom the Department of Radiology (E.L., J.E.L., S.B.S., C.D.P., A.G.).ORCID 0000-0003-4323-7828
S B StraussFrom the Department of Radiology (E.L., J.E.L., S.B.S., C.D.P., A.G.).ORCID 0000-0001-7766-2721
C D PhillipsFrom the Department of Radiology (E.L., J.E.L., S.B.S., C.D.P., A.G.).ORCID 0000-0003-1773-8899
T R CampionDepartment of Population Health Sciences (T.R.C., M.C.).ORCID 0000-0001-7624-769X
B B NaviClinical and Translational Neuroscience Unit (B.B.N., N.S.P., A.E.M., S.M., C.Z., A.G.).ORCID 0000-0001-8424-6128
N S ParikhClinical and Translational Neuroscience Unit (B.B.N., N.S.P., A.E.M., S.M., C.Z., A.G.).ORCID 0000-0002-8802-2380
A E MerklerClinical and Translational Neuroscience Unit (B.B.N., N.S.P., A.E.M., S.M., C.Z., A.G.).ORCID 0000-0002-2211-299X
S MirClinical and Translational Neuroscience Unit (B.B.N., N.S.P., A.E.M., S.M., C.Z., A.G.).ORCID 0000-0001-8954-4802
C ZhangClinical and Translational Neuroscience Unit (B.B.N., N.S.P., A.E.M., S.M., C.Z., A.G.).ORCID 0000-0001-8137-1644
H KamelORCID 0000-0002-5745-0307
M CusickDepartment of Population Health Sciences (T.R.C., M.C.).ORCID 0000-0002-1750-5246
P GoyalFeil Family Brain and Mind Research Institute and Department of Neurology, and Department of Medicine (P.G.), Weill Cornell Medicine, New York, New York.ORCID 0000-0001-7474-3737
A GuptaFrom the Department of Radiology (E.L., J.E.L., S.B.S., C.D.P., A.G.).ORCID 0000-0003-2816-0340
Anna Needs Neuroblastoma Answers · USS.P.E.C.I.E.S. · USCornell University · USThe Quebec Population Health Research Network · CA

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenicstroke (ARCADIA)U01NS095869 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRODERICK, JOSEPH PAUL, KAMEL, HOOMAN · 2017 to 2022
$22.0M
MRI Detection of CarotId Plaques as a mecHanism for Embolic strokes of undeteRmined source (MRI DECIPHER)R01HL144541 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUPTA, AJAY, KAMEL, HOOMAN · 2019 to 2023
$3.9M
Cancer And Risk Of Ischemic StrokeK23NS091395 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI NAVI, BABAK BENJAMIN · 2015 to 2019
$945k
NCATS NIH HHS UL1 TR000457NCATS NIH HHS UL1 TR002384NHLBI NIH HHS R01 HL144541NINDS NIH HHS K23 NS091395NINDS NIH HHS U01 NS095869
6 · The paper itself

Abstract

background and purposeA large spectrum of neurologic disease has been reported in patients with coronavirus disease 2019 (COVID-19) infection. Our aim was to investigate the yield of neuroimaging in patients with COVID-19 undergoing CT or MR imaging of the brain and to describe associated imaging findings. MATERIALS AND

methodsWe performed a retrospective cohort study involving 2054 patients with laboratory-confirmed COVID-19 presenting to 2 hospitals in New York City between March 4 and May 9, 2020, of whom 278 (14%) underwent either CT or MR imaging of the brain. All images initially received a formal interpretation from a neuroradiologist within the institution and were subsequently reviewed by 2 neuroradiologists in consensus, with disputes resolved by a third neuroradiologist.

resultsThe median age of these patients was 64 years (interquartile range, 50-75 years), and 43% were women. Among imaged patients, 58 (21%) demonstrated acute or subacute neuroimaging findings, the most common including cerebral infarctions (11%), parenchymal hematomas (3.6%), and posterior reversible encephalopathy syndrome (1.1%). Among the 51 patients with MR imaging examinations, 26 (51%) demonstrated acute or subacute findings; notable findings included 6 cases of cranial nerve abnormalities (including 4 patients with olfactory bulb abnormalities) and 3 patients with a microhemorrhage pattern compatible with critical illness-associated microbleeds.

conclusionsOur experience confirms the wide range of neurologic imaging findings in patients with COVID-19 and suggests the need for further studies to optimize management for these patients.

Indexed as

AgedBetacoronavirusBrain DiseasesCohort StudiesCoronavirus InfectionsCOVID-19FemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNew York CityPandemicsPneumonia, ViralRetrospective StudiesSARS-CoV-2

Identifiers

PMID32819899
PMCPMC7658823
OpenAlexW3081075792

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.