Evidence map›Paper›PMID 32819355›Full record

ArticleAnnals of clinical microbiology and antimicrobials2020

Nocardia takedensis: a newly recognized pathogen responsible for skin and soft tissue infections.

Romain Lotte, Alicia Chevalier, Sabine Dantas, Nicolas Degand, Alice Gaudart, Pierre-Simon Rörhlich, Laurent Boyer, Veronica Rodriguez-Nava, Pascal Del Giudice, Raymond Ruimy

Abstract readCase Reports
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Romain LotteDepartment of Bacteriology, Nice Academic Hospital, Nice, France. lotte.r@chu-nice.fr.
Alicia ChevalierDepartment of Bacteriology, Nice Academic Hospital, Nice, France.
Sabine DantasResearch Group On Bacterial Opportunistic Pathogens and Environment UMR5557 Écologie Microbienne, French Observatory of Nocardiosis, Institute of Infectious Agents, Hospices Civils de Lyon, Université de Lyon 1, CNRS, VetAgro Sup, Lyon, France.
Nicolas DegandDepartment of Bacteriology, Nice Academic Hospital, Nice, France.
Alice GaudartDepartment of Bacteriology, Nice Academic Hospital, Nice, France.
Pierre-Simon RörhlichUniversité Côte D'Azur, CHU de Nice, Nice, France.
Laurent BoyerUniversité Côte D'Azur, Inserm, C3M, Nice, France.
Veronica Rodriguez-NavaResearch Group On Bacterial Opportunistic Pathogens and Environment UMR5557 Écologie Microbienne, French Observatory of Nocardiosis, Institute of Infectious Agents, Hospices Civils de Lyon, Université de Lyon 1, CNRS, VetAgro Sup, Lyon, France.
Pascal Del GiudiceDepartment of Dermatology and Infectious Diseases, Centre Hospitalier Intercommunal, Fréjus-Saint-Raphaël, Fréjus, France.
Raymond RuimyDepartment of Bacteriology, Nice Academic Hospital, Nice, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nocardia takedensis was first isolated in 2005, from soil in Japan. We report here two cases of lymphangitis in France (2012-2017) caused by N. takedensis both occurring after skin injury while gardening, which enabled its inoculation. The two patients were immunocompromised and successfully treated by an antimicrobial agent active on the isolated strain, trimethoprim-sulfamethoxazole and amoxicillin-clavulanic acid for patient one and patient two, respectively. Our study along with previous ones supports the idea of a newly recognized cutaneous opportunistic pathogen and reinforces the recommendation of using gloves during soil exposure for immunocompromised patients. Lastly, according to data found in the literature, we would recommend trimethoprim-sulfamethoxazole as an efficient empirical antibiotic therapy in case of cutaneous infection caused by N. takedensis.

Indexed as

Aged, 80 and overAnti-Bacterial AgentsFranceGardeningHumansLymphangitisMaleMiddle AgedNocardiaNocardia InfectionsSkin Diseases, InfectiousSoft Tissue InfectionsAnti-Bacterial Agents

Identifiers

PMID32819355
PMCPMC7441698

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.