Evidence map›Paper›PMID 32819210›Full record

ArticleInternational journal of STD & AIDS2020

Uptake, retention, and outcomes in a demonstration project of pre-exposure prophylaxis among female sex workers in public health centers in Senegal.

Moussa Sarr, Daouda Gueye, Aminata Mboup, Ousmane Diouf, Mame D Bousso Bao, Anna Julienne Ndiaye, Birahim P Ndiaye, Stephen E Hawes, Eric Tousset, Abdoulaye Diallo and 6 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Moussa SarrWestat, Inc., Rockville, MD, USA.ORCID 0000-0003-2372-6632
Daouda GueyeIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Aminata MboupIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Ousmane DioufIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Mame D Bousso BaoIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Anna Julienne NdiayeIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Birahim P NdiayeIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Stephen E HawesDepartments of Epidemiology and Global Health, School of Public Health, University of Washington, Seattle, WA, USA.
Eric ToussetAardex Group, Vise, Belgium.ORCID 0000-0001-8798-8127
Abdoulaye DialloWestat, Inc., Rockville, MD, USA.
Fatima JonesWestat, Inc., Rockville, MD, USA.
Coumba T KaneIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.
Safiatou ThiamConseil national de lutte contre le sida (CNLS), Dakar, Sénégal.
Cheikh T NdourDivision de Lutte contre le Sida et les IST, Ministère de la Santé et de l'Action Sociale, Dakar, Sénégal.
Geoffrey S GottliebDepartment of Medicine, Allergy and Infectious Diseases, Center for Emerging and Re-Emerging Infectious Diseases and Department of Global Health, University of Washington, Seattle, WA, USA.
Souleymane MboupIRESSEF: Institut de Recherche en Santé de Surveillance Epidémiologique et de Formations, Dakar, Sénégal.ORCID 0000-0002-7968-3320
Institute of Health Research, Epidemiological Surveillance and Training · SNWestat (United States) · USUniversity of Washington · USComité National de Lutte contre le SIDA · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Senegal pre-exposure prophylaxis (PrEP) Demonstration Project was an open-label cohort study assessing the delivery of daily oral PrEP to HIV-negative female sex workers (FSWs) in four Ministry of Health (MoH)-run clinics in Dakar, Senegal. We assessed uptake, retention in care, and adherence over up to 12 months of follow-up as well as HIV infection rates. Between July and November 2015, 350 individuals were approached and 324 (92.6%) were preliminarily eligible. Uptake was high, with 82.4% of eligible participants choosing to enroll and take PrEP. The mean age of those enrolled was 37.7 years (SD = 8.7), and approximately half had not attended school (41.2%). Among the 267 participants who were prescribed PrEP, 79.9 and 73.4% were retained in PrEP care at 6 and 12 months, respectively. Older age among FSWs was found to be the only significant predictor of lower discontinuation. We did not find significant differences in retention by site, education, condom use, or HIV risk perception. There were no new HIV infections at follow-up. Our results showed evidence of high interest in PrEP and very good PrEP retention rates among FSWs at 12-month follow-up when offered in MoH-run clinics, with older age as the only significant predictor of higher PrEP retention. This highlights the role that these clinics can play in expanding PrEP access nationwide.

Indexed as

AdolescentAdultAnti-HIV AgentsFeasibility StudiesFemaleHIV InfectionsHumansIncidenceMedication AdherenceMiddle AgedPre-Exposure ProphylaxisProgram EvaluationRetention in CareSenegalSex WorkersAnti-HIV AgentsAfricaHIVpreventionsex workerswomen

Identifiers

PMID32819210
PMCPMC7750667
OpenAlexW3081140747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.