ArticleAnimal bioscience2021
Metabolomics comparison of rumen fluid and milk in dairy cattle using proton nuclear magnetic resonance spectroscopy.
Article in Animal bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Rumen-Plasma-Milk Metabolomics Profiling Revealed Metabolic Alterations Associated with Milk Fat Synthesis in Chinese Holstein Cows.Animals : an open access journal from MDPI · 2026Article
- Investigating the potential role of propionylcarnitine in milk pentadecanoic acid synthesis in Chinese holstein dairy cows using multi-omics analysis.BMC genomics · 2026Article
- Effect of negative dietary cation-anion difference (DCAD) diet on primiparous cow metabolomic analysis: Colostrum and milk assay.Journal of advanced veterinary and animal research · 2026Article
- Fecal metabolome in Nelore bulls fed pre- and post-feedlot diets.Tropical animal health and production · 2025Article
- Integrated analysis of rumen metabolomics and metataxonomics to understand changes in metabolic and microbial community in Korean native goats under heat stress.Scientific reports · 2024Article
- Effects of the Use of Rice Grain on Growth Performances, Blood Metabolites, Rumen Fermentation, and Rumen Microbial Community in Fattening Hanwoo Steers.Animals : an open access journal from MDPI · 2023Article
- Blood and milk metabolites of Holstein dairy cattle for the development of objective indicators of a subacute ruminal acidosis.Animal bioscience · 2023Article
- Metabolomics in Acute Kidney Injury: The Clinical Perspective.Journal of clinical medicine · 2023Review
- Metabolomics in Acute Kidney Injury: The Experimental Perspective.Journal of clinical medicine research · 2023Review
- Comparison of metabolites in rumen fluid, urine, and feces of dairy cow from subacute ruminal acidosis model measured by proton nuclear magnetic resonance spectroscopy.Animal bioscience · 2023Article
- Metabolic profiling of serum and urine in lactating dairy cows affected by subclinical ketosis using proton nuclear magnetic resonance spectroscopy.Journal of animal science and technology · 2022Article
- Advances and Trends in Omics Technology Development.Frontiers in medicine · 2022Review
- Effects of seaweed extracts on in vitro rumen fermentation characteristics, methane production, and microbial abundance.Scientific reports · 2021Article
- Metabolomics comparison of serum and urine in dairy cattle using proton nuclear magnetic resonance spectroscopy.Animal bioscience · 2021Article
- Metabolic Profiling of Rumen Fluid and Milk in Lactating Dairy Cattle Influenced by Subclinical Ketosis Using Proton Nuclear Magnetic Resonance Spectroscopy.Animals : an open access journal from MDPI · 2021Article
- Comparative untargeted metabolome analysis of ruminal fluid and feces of Nelore steers (Bos indicus).Scientific reports · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe metabolites that constitute the rumen fluid and milk in dairy cattle were analyzed using proton nuclear magnetic resonance (1H-NMR) spectroscopy and compared with the results obtain for other dairy cattle herds worldwide. The aim was to provide basic dataset for facilitating research on metabolites in rumen fluid and milk.
methodsSix dairy cattle were used in this study. Rumen fluid was collected using a stomach tube, and milk was collected using a pipeline milking system. The metabolites were determined by 1H-NMR spectroscopy, and the obtained data were statistically analyzed by principal component analysis, partial least squares discriminant analysis, variable importance in projection scores, and metabolic pathway data using Metaboanalyst 4.0.
resultsThe total numbers of metabolites in rumen fluid and milk were measured to be 186 and 184, and quantified as 72 and 109, respectively. Organic acid and carbohydrate metabolites exhibited the highest concentrations in rumen fluid and milk, respectively. Some metabolites that have been associated with metabolic diseases (acidosis and ketosis) in cows were identified in rumen fluid, and metabolites associated with ketosis, somatic cell production, and coagulation properties were identified in milk.
conclusionThe metabolites measured in rumen fluid and milk could potentially be used to detect metabolic diseases and evaluate milk quality. The results could also be useful for metabolomic research on the biofluids of ruminants in Korea, while facilitating their metabolic research.
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