Why Have Two When One Will Do? Comparing Task Representations across Amygdala and Prefrontal Cortex in Single Neurons and Neuronal Populations.

Alexander D Jacob, Sheena A Josselyn

Abstract readComment

In one paragraph

Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Regional specialization in prefrontal cortex manifests in the reliability of task progression codes.Neuron · 2026
Article
Single voxel autocorrelation uncovers gradients of temporal dynamics in the hippocampus and entorhinal cortex during rest and navigation.Cerebral cortex (New York, N.Y. : 1991) · 2023
Article

4 · The record

Corrections and comments

Comment on
Different Multidimensional Representations across the Amygdalo-Prefrontal Network during an Approach-Avoidance Task.2020

5 · Who and what money

Authors and funding

2 authors.

Alexander D JacobProgram in Neurosciences & Mental Health, Hospital for Sick Children, 555 University Ave., Toronto, ON M5G 1X8, Canada; Department of Psychology, University of Toronto, Toronto, ON M5G 1X8, Canada.

Sheena A JosselynProgram in Neurosciences & Mental Health, Hospital for Sick Children, 555 University Ave., Toronto, ON M5G 1X8, Canada; Institute of Medical Sciences, University of Toronto, Toronto, ON M5G 1X9, Canada; Department of Physiology, University of Toronto, Toronto, ON M5G 1X8, Canada; Department of Psychology, University of Toronto, Toronto, ON M5G 1X8, Canada; Brain, Mind & Consciousness Program, Canadian Institute for Advanced Research (CIFAR), Toronto, ON M5G 1M1, Canada. Electronic address: sheena.josselyn@sickkids.ca.

Funding

The Role of Neuronal Ensembles Supporting Auditory Fear Conditioning (Engrams) in the Amygdala in Memory Formation, Generalization and ExtinctionR01MH119421 · NIMH · HOSPITAL FOR SICK CHLDRN (TORONTO) · PI FRANKLAND, PAUL, JOSSELYN, SHEENA A · 2019 to 2023

$1.7M

CIHR FDN-388455NIMH NIH HHS R01 MH119421

6 · The paper itself

Abstract

Many brain areas represent aspects of learned behavior. How do representations differ between regions? In this issue of Neuron, Kyriazi et al. (2020) show how the amygdala and prefrontal cortex use distinct strategies to code features of a complex task.

Indexed as

AmygdalaPrefrontal CortexBrainNeurons

Identifiers

PMID32818473

DOI10.1016/j.neuron.2020.07.038

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.