ArticleEmerging infectious diseases2020
Molecular Description of a Novel Orientia Species Causing Scrub Typhus in Chile.
Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.
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Who cites it
66 citing papers in PubMed, 4 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Global and regional seroprevalence, incidence, mortality of, and risk factors for scrub typhus: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Pooled it
- Unveiling the burden of scrub typhus in acute febrile illness cases across India: A systematic review & meta-analysis.The Indian journal of medical research · 2024Pooled it
- Systematic review of the scrub typhus treatment landscape: Assessing the feasibility of an individual participant-level data (IPD) platform.PLoS neglected tropical diseases · 2021Pooled it
- Prevalence of malaria and scrub typhus co-infection in febrile patients: a systematic review and meta-analysis.Parasites & vectors · 2021Pooled it
- High levels of antisense transcription from numerous genes in the obligate intracellular bacteriumJournal of bacteriology · 2026Article
- Transformation and allelic exchange inmBio · 2026Article
- Acute respiratory distress syndrome in scrub typhus: a systematic review and meta-analysis.Infection · 2026Review
- Tick cells as a tractable arthropod model for studyingApplied and environmental microbiology · 2026Article
- Transformation and allelic exchange inbioRxiv : the preprint server for biology · 2026Article
- Rickettsiosis: existing advances and future opportunities for the development of vaccines.Veterinary research communications · 2026Review
- Surveillance of vector-borne infections: Dogs as sentinel animals forOne health (Amsterdam, Netherlands) · 2026Article
- A Compact Closed Genome ofPathogens (Basel, Switzerland) · 2026Article
- Longitudinal peripheral blood immune profiling reveals dynamic changes of five major immune cell lineages and their clinical associations in pediatric scrub typhus.Frontiers in immunology · 2026Article
- Differential spleen immune signatures and germinal center responses during acute infection withFrontiers in immunology · 2026Article
- Geographic and Orientia infection status influence on the bacterial microbiome of free-living chiggers in North Carolina, USA.PloS one · 2026Article
- Molecular detection of Orientia tsutsugamushi infection in bats from the China-Myanmar border.PLoS neglected tropical diseases · 2026Article
- Environmental Conditions and Mite Vectors Shape the Spatiotemporal Patterns of Scrub Typhus in Guangdong Province, Mainland China.Tropical medicine and infectious disease · 2025Article
- Influence of meteorological factors on scrub typhus in Southeast China: a study across 100 districts in Jiangxi Province.Tropical medicine and health · 2025Article
- Associations between meteorological factors and scrub typhus incidence: a systematic review and meta-analysis of linear and nonlinear dose-response relationships.Tropical medicine and health · 2025Article
- Estimating scrub typhus and murine typhus incidence among adolescents and adults in Yangon, Myanmar.Tropical medicine & international health : TM & IH · 2025Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scrub typhus is a potentially fatal rickettsiosis caused by Orientia species intracellular bacteria of the genus Orientia. Although considered to be restricted to the Asia Pacific region, scrub typhus has recently been discovered in southern Chile. We analyzed Orientia gene sequences of 16S rRNA (rrs) and 47-kDa (htrA) from 18 scrub typhus patients from Chile. Sequences were ≥99.7% identical among the samples for both amplified genes. Their diversity was 3.1%-3.5% for rrs and 11.2%-11.8% for htrA compared with O. tsusugamushi and 3.0% for rrs and 14.8% for htrA compared with Candidatus Orientia chuto. Phylogenetic analyses of both genes grouped the specimens from Chile in a different clade from other Orientia species. Our results indicate that Orientia isolates from Chile constitute a novel species, which, until they are cultivated and fully characterized, we propose to designate as Candidatus Orientia chiloensis, after the Chiloé Archipelago where the pathogen was identified.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.