Evidence map›Paper›PMID 32818210›Full record

ArticleResearch square2020

Elovanoid-N32 or RvD6-isomer decrease ACE2 and binding of S protein RBD after injury or INFγ in the eye.

Thang L Pham, Jiucheng He, Azucena H Kakazu, Jorgelina Calandria, Khanh V Do, Robert Nshimiyimana, Nicos A Petasis, Haydee E P Bazan, Nicolas G Bazan

Open access · goldAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Thang L PhamLouisiana State University Health New Orleans.
Jiucheng HeLouisiana State University Health New Orleans.
Azucena H KakazuLouisiana State University Health New Orleans.
Jorgelina CalandriaLouisiana State University Health New Orleans.
Khanh V DoLouisiana State University Health New Orleans.
Robert NshimiyimanaUniversity of Southern California.
Nicos A PetasisUniversity of Southern California.
Haydee E P BazanLouisiana State University Health New Orleans.ORCID 0000-0001-7172-7870
Nicolas G BazanLouisiana State University Health New Orleans.ORCID 0000-0002-9243-5444
Louisiana State University Health Sciences Center New Orleans · USUniversity of Southern California · US

Funding

Lipid Mediators in Corneal Nerve RegenerationR01EY019465 · NEI · LSU HEALTH SCIENCES CENTER · PI BAZAN, HAYDEE E.P. · 2009 to 2021
$4.0M
NEI NIH HHS R01 EY019465
6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that causes coronavirus disease 2019 (COVID-19) has resulted in a pandemic affecting the most vulnerable in society, triggering a public health crisis and economic tall around the world. Effective treatments to mitigate this virus infection are needed. Since the eye is a route of virus entrance, we use an

Indexed as

ACE2 receptorCytokine stormHyper-inflammationLipid mediatorsOcular surfaceSARS-CoV-2SenescenceSpike protein

Identifiers

PMID32818210
PMCPMC7430585
OpenAlexW3081505919

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.