ArticleOpen forum infectious diseases2020
Management and Outcome of Left Ventricular Assist Device Infections in Patients Undergoing Cardiac Transplantation.
Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Enterococcal Infections in Left Ventricular Assist Device Recipients: Two Clinical Cases and Systematic Review.Pathogens (Basel, Switzerland) · 2026Pooled it
- Review
- Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices.JHLT open · 2025Article
- Infections in Patients with Mechanical Circulatory Support.Infectious disease clinics of North America · 2024Review
- Incidence, risk factors and clinical outcome of multidrug-resistant organisms after heart transplantation.World journal of transplantation · 2024Article
- Special Considerations for Advanced Heart Failure Surgeries: Durable Left Ventricular Devices and Heart Transplantation.Journal of cardiovascular development and disease · 2024Review
- IgM-enriched immunoglobulin as adjuvant therapy for heart transplant after infection of left ventricular assist devices.ESC heart failure · 2022Article
- Mechanical Circulatory Support in Cardiovascular Surgical Patients: Single Center Practice and Experience.Reviews in cardiovascular medicine · 2022Article
- Continuous-flow left ventricular assist device systems infections: current outcomes and management strategies.Annals of cardiothoracic surgery · 2021Review
- Management of Bloodstream Infections in Left Ventricular Assist Device Recipients: To Suppress, or Not to Suppress?Open forum infectious diseases · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative management of patients undergoing cardiac transplantation with an infected left ventricular assist device (LVAD) is unclear.
methodsWe retrospectively screened all adults with an LVAD who underwent cardiac transplantation at our institution from 2010 through 2018. We selected all cases of LVAD-specific and LVAD-related infections who were receiving antimicrobial therapy as initial treatment course or chronic suppression at the time of cardiac transplantation. Non-LVAD infections, superficial driveline-infection, or concurrent use of right ventricular assist device or extracorporeal membrane oxygenation device were excluded.
resultsA total of 54 cases met study criteria with 18 of 54 (33.6%) classified as LVAD- specific or related infections and 36 of 54 (66.6%) as noninfected. cases of lvad infection had a higher median charlson comorbidity Index score at the time of transplantation compared with noninfected cases (
conclusionsPatients with an LVAD-specific infection were treated with 2 weeks of pathogen-directed therapy postheart transplant without any relapses. For those without LVAD-specific infection or uncomplicated LVAD-related bacteremia who had completed antimicrobial therapy pretransplant, antibiotics were discontinued after standard perioperative prophylaxis and no relapses were observed.
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