Evidence map›Paper›PMID 32818101›Full record

ArticleTranslational vision science & technology2020

An Automated Method for Assessing Topographical Structure-Function Agreement in Abnormal Glaucomatous Regions.

Emmanouil Tsamis, Nikhil K Bommakanti, Ashley Sun, Kaveri A Thakoor, Carlos Gustavo De Moraes, Donald C Hood

Open access · goldAbstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Emmanouil TsamisDepartment of Psychology, Columbia University, New York, NY, USA.
Nikhil K BommakantiDepartment of Ophthalmology, Columbia University, New York, NY, USA.
Ashley SunDepartment of Psychology, Columbia University, New York, NY, USA.
Kaveri A ThakoorDepartment of Psychology, Columbia University, New York, NY, USA.
Carlos Gustavo De MoraesDepartment of Ophthalmology, Columbia University, New York, NY, USA.
Donald C HoodDepartment of Psychology, Columbia University, New York, NY, USA.
Columbia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To develop an automated/objective method for topographically comparing abnormal regions on optical coherence tomography (OCT) and visual field (VF) tests of eyes with early glaucoma. Methods: A custom R program was developed that allows for both visualization and automatic assessment of the topographical agreement between functional (24-2 and/or 10-2 VF) and structural (widefield OCT retinal nerve fiber layer and/or retinal ganglion cell layer) deviation/probability maps. It was optimized using information from 98 eyes: 53 diagnosed as "definitely glaucoma" (DG) and 45 recruited as healthy (H) controls. Different pairs of abnormal VF ( Results: A criterion of two aS-aF locations with "OCT <10% and VF <5%" on VF pattern deviation (PD) probability and OCT deviation/probability maps yielded high overall agreement (92%) with high aS-aF agreement for the DG eyes (89%) and high aS-aF nonagreement for the H eyes (95%). Total deviation probability maps achieved slightly lower performance than PD maps. Conclusions: The method described here can automatically and objectively evaluate aS-aF agreement with a direct comparison of abnormal regions of function and structure. Translational Relevance: As glaucoma diagnosis often involves assessing structure-function agreement, this technique can overcome subjectivity in this assessment.

Indexed as

GlaucomaOptic Nerve DiseasesHumansNerve FibersVisual FieldsVisual Field Testsfunctionglaucomaoptical coherence tomographyperimetrystructurevisual fields

Identifiers

PMID32818101
PMCPMC7396198
OpenAlexW3012186699

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.