ReviewEFORT open reviews2020
Kinematic alignment in total knee arthroplasty.
Review in EFORT open reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06835621 (Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty. A Randomized Controlled Trial.), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of Functional Recovery Between Restricted Inverse Kinematic Alignment and Adjusted Mechanical Alignment With Robotic-assisted Unilateral Total Knee Arthroplasty. A Randomized Controlled Trial.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Mechanical versus kinematic alignment for total knee arthroplasty: a meta-analysis.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Comparison of Patellar Tracking Following Kinematic Alignment Versus Mechanical Alignment Total Knee Arthroplasty via the Mini-Subvastus Approach.Orthopaedic surgery · 2025Trial
- Restoring tibial obliquity for kinematic alignment in total knee arthroplasty: conventional versus patient-specific instrumentation.Archives of orthopaedic and trauma surgery · 2023Trial
- Kinematic alignment versus mechanical alignment in total knee arthroplasty: a systematic review and meta-analysis of medium to long-term outcomes.Musculoskeletal surgery · 2026Review
- Patellar tracking and patellar tilt in kinematic versus mechanical knees.Journal of experimental orthopaedics · 2026Article
- Mechanically aligned total knee arthroplasty demonstrates acceptable outcomes in obese patients, with insufficient evidence for alternative alignment strategies: A systematic review.Journal of experimental orthopaedics · 2026Review
- Kinematic Alignment in Total Knee Arthroplasty of Varus Knees Minimises Distal Ankle Compensatory Changes Compared with Mechanical Alignment.Journal of clinical medicine · 2026Article
- Robotic-Assisted Total Knee Arthroplasty: Current Evidence on PROMs, Functional Outcomes, Neuromotor Recovery, and Complications-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Mixed-Reality Guidance for Total Knee Arthroplasty Is Associated With More Accurate Femoral Resection but Longer Operative Time Compared to Accelerometer-Based Guidance.Arthroplasty today · 2026Article
- Sex-related differences in final knee balance during robotic-assisted unicompartmental knee arthroplasty.Archives of orthopaedic and trauma surgery · 2026Article
- Restricted kinematic alignment in total knee arthroplasty achieves equivalent or superior functional outcomes to mechanical alignment without compromising implant survivorship: A systematic review.Journal of orthopaedics · 2026Review
- Kinematic alignment preserves the mid-flexion trochlear line orientation in total knee arthroplasty: A prospective analysis from the FP-UCBM Knee Study Group.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Effect of femoral component design and quadriceps load on patellofemoral kinematics after total knee arthroplasty: an in vitro cadaveric study.Knee surgery & related research · 2026Article
- Alignment Philosophies in Total Knee Arthroplasty: A Comprehensive Narrative Review.Arthroplasty today · 2026Article
- Excellent Short-Term Outcomes After Kinematic Alignment, Medial-Pivot Total Knee Arthroplasty for Isolated Patellofemoral Osteoarthritis.Arthroplasty today · 2026Article
- Prospective observational study of coronal and sagittal alignment after primary total knee arthroplasty and their association with early (3-month) functional outcomes.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- Posterior condylar offset and clinical outcomes in medial pivot total knee arthroplasty: A comparison of mechanical and kinematic alignment.Journal of experimental orthopaedics · 2026Article
- Kinematically aligned total knee arthroplasty via subvastus approach using the Mako® 2.0 total knee system: a surgical technique.Frontiers in surgery · 2026Article
- Are current total knee arthroplasty implants tested and approved for personalised alignment?Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Kinematically aligned robotic total knee arthroplasty for post-traumatic femoral recurvatum with hardware retention: a case report.Journal of surgical case reports · 2025Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kinematic alignment (KA) is an alternative philosophy for aligning a total knee replacement (TKR) which aims to restore all three kinematic axes of the native knee.Many of the studies on KA have actually described non-KA techniques, which has led to much confusion about what actually fits the definition of KA.Alignment should only be measured using three-dimensional cross-sectional imaging. Many of the studies looking at the influence of implants/limb alignment on total knee arthroplasty outcomes are of limited value because of the use of two-dimensional imaging to measure alignment, potentially leading to inaccuracy.No studies have shown KA to be associated with higher complication rates or with worse implant survival; and the clinical outcomes following KA tend to be at least as good as mechanical alignment.Further high-quality multi-centre randomized controlled trials are needed to establish whether KA provides better function and without adversely impacting implant survival. Cite this article:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.