ReviewTropical medicine and health2020
Ethnobotany, ethnopharmacology, and phytochemistry of traditional medicinal plants used in the management of symptoms of tuberculosis in East Africa: a systematic review.
Review in Tropical medicine and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Phytochemical Analysis and Bioactivities ofPlants (Basel, Switzerland) · 2026Article
- Traditional medicinal plant based remedies for common ailments in Menz Keya Gebreal District, North Shewa Zone, Ethiopia.BMC complementary medicine and therapies · 2025Article
- Ethnobotanical survey and antimycobacterial activities of plants used against tuberculosis in Lubumbashi, DR Congo.Tropical medicine and health · 2025Article
- Antioxidant: Antimycobacterial and Antibiofilm Activities of Acetone Extract and SubfractionAntibiotics (Basel, Switzerland) · 2024Article
- Acute and subacute toxicity profile of ethanolic stem bark extract ofToxicology reports · 2024Article
- Antibacterial Activity and Proposed Mode of Action of Extracts from Selected Zimbabwean Medicinal Plants againstAdvances in pharmacological and pharmaceutical sciences · 2024Article
- Medicinal plants used in the management of cancers by residents in the Elgon Sub-Region, Uganda.BMC complementary medicine and therapies · 2023Article
- Ethnomedicinal plants used for malaria treatment in Rukungiri District, Western Uganda.Tropical medicine and health · 2023Article
- Traditional medicinal plants used in the treatment of tuberculosis in Ethiopia: A systematic review.Heliyon · 2022Review
- An Annotated Inventory of Tanzanian Medicinal Plants Traditionally Used for the Treatment of Respiratory Bacterial Infections.Plants (Basel, Switzerland) · 2022Review
- Ethnobotanical plants used in the management of symptoms of tuberculosis in rural Uganda.Tropical medicine and health · 2021Article
- Sub-Acute Toxicity Effects of Methanolic Stem Bark Extract ofFrontiers in pharmacology · 2021Article
- Intraspecific Variation of Phytochemicals, Antioxidant, and Antibacterial Activities of Different Solvent Extracts ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Ethnobotanical Documentation, Phytochemical Screening, and Cytotoxicity Evaluation of Medicinal Plants Used to Manage Snakebite Envenomation in Mwingi West Subcounty, Kenya.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Review
- Review of Herbal Medicinal Plants Used in the Management of Cancers in the East Africa Region from 2019 to 2023.Integrative cancer therapiesReview
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMany studies on the treatment of tuberculosis (TB) using herbal medicines have been undertaken in recent decades in East Africa. The details, however, are highly fragmented. The purpose of this study was to provide a comprehensive overview of the reported medicinal plants used to manage TB symptoms, and to analyze scientific reports on their effectiveness and safety.
methodA comprehensive literature search was performed in the major electronic databases regarding medicinal plants used in the management of TB in East Africa. A total of 44 reports were retrieved, and data were collected on various aspects of the medicinal plants such as botanical name, family, local names, part(s) used, method of preparation, efficacy, toxicity, and phytochemistry. The data were summarized into percentages and frequencies which were presented as tables and graphs.
resultsA total of 195 species of plants belonging to 68 families and 144 genera were identified. Most encountered species were from Fabaceae (42.6%), Lamiaceae (19.1%), Asteraceae (16.2%), and Euphorbiaceae (14.7%) families. Only 36 medicinal plants (18.5%) have been screened for antimycobacterial activity. Out of these, 31 (86.1%) were reported to be bioactive with minimum inhibitory concentrations ranging from 47 to 12,500 μg/ml. Most tested plant extracts were found to have acceptable acute toxicity profiles with cytotoxic concentrations on normal mammalian cells greater than 200 μg/ml. The most commonly reported phytochemicals were flavonoids, terpenoids, alkaloids, saponins, cardiac glycosides, and phenols. Only
conclusionEast Africa has a rich diversity of medicinal plants that have been reported to be effective in the management of symptoms of TB. More validation studies are required to promote the discovery of antimycobacterial drugs and to provide evidence for standardization of herbal medicine use.
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