Evidence map›Paper›PMID 32817964›Full record

ArticlemedRxiv : the preprint server for health sciences2020

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning.

Skylar W Marvel, John S House, Matthew Wheeler, Kuncheng Song, Yihui Zhou, Fred A Wright, Weihsueh A Chiu, Ivan Rusyn, Alison Motsinger-Reif, David M Reif

Open access · greenAbstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Skylar W MarvelBioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
John S HouseBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.
Matthew WheelerBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.
Kuncheng SongBioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
Yihui ZhouBioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
Fred A WrightBioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
Weihsueh A ChiuVeterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77845, USA.
Ivan RusynVeterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77845, USA.
Alison Motsinger-ReifBiostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA.
David M ReifBioinformatics Research Center, Department of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
North Carolina State University · USNational Institute of Environmental Health Sciences · USTexas A&M University · US

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Thomas Joseph McDonald · 2017 to 2026
$21.2M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Andrew R. Binder · 2015 to 2026
$18.3M
Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Weston W Porter · 2019 to 2026
$13.0M
Uncovering the Mechanisms of PFAS-induced ImmunotoxicityP42ES031009 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI PLANCHART, ANTONIO J. · 2020 to 2024
$9.3M
COVID-19 Pandemic VulnerabilityZIAES103352 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MOTSINGER-REIF, ALISON · 2020 to 2023
$2.9M
Intramural NIH HHS ZIA ES103352NIEHS NIH HHS P30 ES025128NIEHS NIH HHS P30 ES029067NIEHS NIH HHS P42 ES027704NIEHS NIH HHS P42 ES031009
6 · The paper itself

Abstract

backgroundWhile the COVID-19 pandemic presents a global challenge, the U.S. response places substantial responsibility for both decision-making and communication on local health authorities, necessitating tools to support decision-making at the community level.

objectivesWe created a Pandemic Vulnerability Index (PVI) to support counties and municipalities by integrating baseline data on relevant community vulnerabilities with dynamic data on local infection rates and interventions. The PVI visually synthesizes county-level vulnerability indicators, enabling their comparison in regional, state, and nationwide contexts.

methodsWe describe the data streams used and how these are combined to calculate the PVI, detail the supporting epidemiological modeling and machine-learning forecasts, and outline the deployment of an interactive web Dashboard. Finally, we describe the practical application of the PVI for real-world decision-making.

resultsConsidering an outlook horizon from 1 to 28 days, the overall PVI scores are significantly associated with key vulnerability-related outcome metrics of cumulative deaths, population adjusted cumulative deaths, and the proportion of deaths from cases. The modeling results indicate the most significant predictors of case counts are population size, proportion of black residents, and mean PM DISCUSSION: The COVID-19 PVI Dashboard monitors multiple data streams to communicate county-level trends and vulnerabilities and facilitates decision-making and communication among government officials, scientists, community leaders, and the public to enable effective and coordinated action to combat the pandemic.

Identifiers

PMID32817964
PMCPMC7430608
OpenAlexW3048695905

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.