Evidence map›Paper›PMID 32817933›Full record

ArticlebioRxiv : the preprint server for biology2020

Hydroxychloroquine: mechanism of action inhibiting SARS-CoV2 entry.

Zixuan Yuan, Mahmud Arif Pavel, Hao Wang, Scott B Hansen

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 19 citations in OpenAlex.

  1. Targeting Lipid Rafts as a Strategy Against Coronavirus.Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zixuan YuanDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida, 33458, USA.
Mahmud Arif PavelDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida, 33458, USA.
Hao WangDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida, 33458, USA.
Scott B HansenDepartment of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida, 33458, USA.
Scripps Research Institute · US

Funding

The role of lipid raft disruption in the activation of TREK-1 channels by anestheticsR01NS112534 · NINDS · UNIVERSITY OF FLORIDA · PI HANSEN, SCOTT B · 2019 to 2023
$2.2M
NINDS NIH HHS R01 NS112534
6 · The paper itself

Abstract

Hydroxychloroquine (HCQ) has been proposed in the treatment of SARS-coronavirus 2 (SARS-CoV-2) infection, albeit with much controversy.

Identifiers

PMID32817933
PMCPMC7430563
OpenAlexW3049585594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.