Evidence map›Paper›PMID 32817909›Full record

ArticleBioactive materials2021

ROS-responsive capsules engineered from EGCG-Zinc networks improve therapeutic angiogenesis in mouse limb ischemia.

Zuoguan Chen, Jianwei Duan, Yongpeng Diao, Youlu Chen, Xiaoyu Liang, Huiyang Li, Yuqing Miao, Qing Gao, Liang Gui, Xiaoli Wang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 109 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Zuoguan ChenDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Jianwei DuanTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Yongpeng DiaoDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Youlu ChenTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Xiaoyu LiangTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Huiyang LiTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Yuqing MiaoDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Qing GaoDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Liang GuiDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Xiaoli WangTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Jing YangTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, 300192, PR China.
Yongjun LiDepartment of Vascular Surgery, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine. Chinese Academy of Medical Sciences and Peking Union Medical College. Graduate School of Peking Union Medical College, Beijing, 100730, PR China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The successful treatment of limb ischemia requires that promote angiogenesis along with microenvironment improvement. Zinc ions have been reported to stimulate angiogenesis, but application was limited to the toxicity concerns. We hypothesized that zinc based metal-EGCG capsule (EGCG/Zn Ps) can achieve sustained release Zn

Indexed as

AngiogenesisGreen tea polyphenolLimb ischemia diseasePolyphenol metal networksZinc

Identifiers

PMID32817909
PMCPMC7415630
OpenAlexW3048348838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.