Evidence map›Paper›PMID 32817816›Full record

ArticleLeukemia research reports2020

Targeted therapy for medullary and extramedullary relapse of FLT3-ITD acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation.

Takahiro Kumode, Shinya Rai, Hirokazu Tanaka, J Luis Espinoza, Hiroaki Kakutani, Yosaku Watatani, Shuji Minamoto, Yasuhiro Taniguchi, Shoko Nakayama, Yasuyoshi Morita and 2 more

Open access · goldAbstract read
In one paragraph

Article in Leukemia research reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Takahiro KumodeDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Shinya RaiDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Hirokazu TanakaDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
J Luis EspinozaDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Hiroaki KakutaniDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Yosaku WatataniDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Shuji MinamotoDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Yasuhiro TaniguchiDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Shoko NakayamaDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Yasuyoshi MoritaDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Takashi AshidaDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Itaru MatsumuraDepartment of Hematology and Rheumatology, Kindai University Hospital, Faculty of Medicine, Osakasayama, Japan.
Kindai University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case with extramedullary tumors affecting the supraclavicular region that presented as a relapse of acute myeloid leukemia (AML) with FLT3-ITD mutation after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Treatment with gilteritinib resulted in remarkable response with disappearance of both the medullary and extramedullary tumors. Subsequently, a 2nd allo-HSCT was performed in an attempt to cure his AML and complete molecular response has been sustained with gilteritinib resumption without worsening GVHD. Targeted therapy with gilteritinib for medullary and extramedullary relapse of

Indexed as

Acute myeloid leukemiaFLT3-ITDGilteritinibMyeloid sarcoma

Identifiers

PMID32817816
PMCPMC7426564
OpenAlexW3047917440

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.