Evidence map›Paper›PMID 32817543›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break.

Kevin Li, Gabriel Bronk, Jane Kondev, James E Haber

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. The Role of Arp2/3 in End-Resection During DNA Double-Strand Break Repair.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  3. The BaeS/BaeR two-component system enhancesFrontiers in cellular and infection microbiology · 2026
    Article
  4. Article
  5. PsDMAP1/PsTIP60-regulated H4K16ac is required for ROS-dependent virulence adaptation ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kevin LiDepartment of Physics, Brandeis University, Waltham, MA 02454.ORCID 0000-0002-5290-2378
Gabriel BronkDepartment of Physics, Brandeis University, Waltham, MA 02454.
Jane KondevDepartment of Physics, Brandeis University, Waltham, MA 02454; kondev@brandeis.edu haber@brandeis.edu.
James E HaberDepartment of Biology, Brandeis University, Waltham, MA 02454; kondev@brandeis.edu haber@brandeis.edu.ORCID 0000-0002-1878-0610
Brandeis University · US

Funding

DNA Damage Response and Repair of a Broken ChromosomeR35GM127029 · NIGMS · BRANDEIS UNIVERSITY · PI JAMES E HABER · 2018 to 2026
$8.6M
Recombination Mechanisms in Yeast Cell DifferentiationR37GM020056 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 2007 to 2016
$5.5M
RECOMBINATION MECHANISMS IN YEAST CELL DIFFERENTIATIONR01GM020056 · NIGMS · BRANDEIS UNIVERSITY · PI HABER, JAMES E · 1985 to 2006
$3.4M
NIGMS NIH HHS R01 GM020056NIGMS NIH HHS R35 GM127029NIGMS NIH HHS R37 GM020056
6 · The paper itself

Abstract

One of the hallmarks of DNA damage is the rapid spreading of phosphorylated histone H2A (γ-H2AX) around a DNA double-strand break (DSB). In the budding yeast

Indexed as

DNA Breaks, Double-StrandedAdaptor Proteins, Signal TransducingBayes TheoremCell Cycle ProteinsChromatin ImmunoprecipitationDiffusionHistonesIntracellular Signaling Peptides and ProteinsPhosphorylationProtein Serine-Threonine KinasesSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdaptor Proteins, Signal TransducingCell Cycle ProteinsHistonesIntracellular Signaling Peptides and ProteinsLCD1 protein, S cerevisiaeMEC1 protein, S cerevisiaeProtein Serine-Threonine Kinasesrad9 proteinSaccharomyces cerevisiae ProteinsTEL1 protein, S cerevisiaeBayesian model selectionchromatin dynamicsdouble-strand breakYeast ATM and ATR protein kinasesγ-H2AX

Identifiers

PMID32817543
PMCPMC7474660
OpenAlexW3067233643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.