Evidence map›Paper›PMID 32817489›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Cdc48 cofactor Shp1 regulates signal-induced SCF

Linda Lauinger, Karin Flick, James L Yen, Radhika Mathur, Peter Kaiser

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Distinct Stress Regulators in the CRL Family: Emerging Roles of F-Box Proteins: Cullin-RING Ligases and Stress-Sensing.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Linda LauingerDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.ORCID 0000-0003-2543-8562
Karin FlickDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.ORCID 0000-0003-2195-5503
James L YenDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.ORCID 0000-0002-0478-9526
Radhika MathurDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700.
Peter KaiserDepartment of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697-1700 pkaiser@uci.edu.

Funding

Ubiquitin SignalingR01GM066164 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI KAISER, PETER · 2002 to 2022
$7.4M
NIGMS NIH HHS R01 GM066164
6 · The paper itself

Abstract

Organisms can adapt to a broad spectrum of sudden and dramatic changes in their environment. These abrupt changes are often perceived as stress and trigger responses that facilitate survival and eventual adaptation. The ubiquitin-proteasome system (UPS) is involved in most cellular processes. Unsurprisingly, components of the UPS also play crucial roles during various stress response programs. The budding yeast SCF

Indexed as

CadmiumF-Box ProteinsIntracellular Signaling Peptides and ProteinsMutationProtein DomainsProtein MultimerizationSaccharomyces cerevisiae ProteinsSaccharomycetalesStress, PhysiologicalUbiquitin-Protein Ligase ComplexesValosin Containing ProteinCadmiumCDC48 protein, S cerevisiaeF-Box ProteinsIntracellular Signaling Peptides and ProteinsMET30 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsSHP1 protein, S cerevisiaeUbiquitin-Protein Ligase ComplexesValosin Containing ProteinCdc48/p97SCF-Met30Shp1

Identifiers

PMID32817489
PMCPMC7474596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.