Evidence map›Paper›PMID 32817440›Full record

ArticlePediatrics2020

Maternal Depression in Early Childhood and Developmental Vulnerability at School Entry.

Elizabeth Wall-Wieler, Leslie L Roos, Ian H Gotlib

Abstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Effects of an Early Home Visiting Program on Maternal Depression.Administration and policy in mental health · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Elizabeth Wall-WielerDepartments of Pediatrics and ewallwie@stanford.edu.
Leslie L RoosPsychology, Stanford University, Stanford, California; and.
Ian H GotlibDepartments of Pediatrics and.

Funding

Psychobiological Mechanisms Underlying the Association Between Early Life Stress and Depression Across AdolescenceR37MH101495 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB · 2018 to 2026
$6.6M
CIHR PJT-162111NIMH NIH HHS R37 MH101495
6 · The paper itself

Abstract

objectivesTo assess the relation between exposure to maternal depression before age 5 and 5 domains of developmental vulnerability at school entry, overall, and by age at exposure.

methodsThis cohort study included all children born in Manitoba, Canada, who completed the Early Development Instrument between 2005 and 2016 (

resultsChildren exposed to maternal depression before age 5 had a 17% higher risk of having at least 1 developmental vulnerability at school entry than did children not exposed to maternal depression before age 5. Exposure to maternal depression was most strongly associated with difficulties in social competence (adjusted relative risk [aRR] = 1.28; 95% confidence interval [CI]: 1.20-1.38), physical health and well-being (aRR = 1.28; 95% CI: 1.20-1.36), and emotional maturity (aRR = 1.27; 95% CI: 1.18-1.37). For most developmental domains, exposure to maternal depression before age 1 and between ages 4 and 5 had the strongest association with developmental vulnerability.

conclusionsOur finding that children exposed to maternal depression are at higher risk for developmental vulnerability at school entry is consistent with previous findings. We extended this literature by documenting that the adverse effects of exposure to maternal depression are specific to particular developmental domains and that these effects vary depending on the age at which the child is exposed to maternal depression.

Indexed as

Health StatusSocial SkillsChild, PreschoolCohort StudiesConfidence IntervalsDepressionDepression, PostpartumDevelopmental DisabilitiesFemaleHumansInfantManitobaMothersRiskSiblingsSocioeconomic Factors

Identifiers

PMID32817440
PMCPMC7461243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.