Evidence map›Paper›PMID 32817370›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Cutting Edge: Inhibition of Glycogen Synthase Kinase 3 Activity Induces the Generation and Enhanced Suppressive Function of Human IL-10

Hao Cheng, Lingbiao Wang, Biaolong Yang, Dan Li, Xiaoxia Wang, Xinnan Liu, Na Tian, Qianru Huang, Ru Feng, Zhengting Wang and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Expansion of B10 cellsInternational journal of molecular medicine · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Characterization of novel CD8Cellular and molecular life sciences : CMLS · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. The Dynamic Role of FOXP3Frontiers in immunology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Hao ChengKey Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China.ORCID 0000-0002-5091-3874
Lingbiao WangDivision of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Biaolong YangDepartment of Medical Oncology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Dan LiShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Xiaoxia WangShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Xinnan LiuShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Na TianDepartment of Rheumatology and Immunology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China; and.ORCID 0000-0003-4361-0565
Qianru HuangShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ru FengShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0002-1003-0479
Zhengting WangDepartment of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Rui LiangShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Sheng-Ming DaiDepartment of Rheumatology and Immunology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China; and.ORCID 0000-0001-8876-4205
Ling LvDivision of Rheumatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Ji WuKey Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China; jiwu@sjtu.edu.cn doctorzangys@163.com binli@shsmu.edu.cn.
Yuan-Sheng ZangDepartment of Medical Oncology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China; jiwu@sjtu.edu.cn doctorzangys@163.com binli@shsmu.edu.cn.
Bin LiShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; jiwu@sjtu.edu.cn doctorzangys@163.com binli@shsmu.edu.cn.ORCID 0000-0002-7640-8884
Shanghai Jiao Tong University · CNFudan University · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IL-10 is critical for Foxp3

Indexed as

AnimalsCells, CulturedForkhead Transcription FactorsGlycogen Synthase Kinase 3HeterograftsHumansImmune ToleranceIndolesInterleukin-10Lymphocyte ActivationMaleimidesMiceMice, KnockoutPositive Regulatory Domain I-Binding Factor 1Promoter Regions, GeneticProto-Oncogene Proteins c-mafForkhead Transcription FactorsFOXP3 protein, humanGlycogen Synthase Kinase 3IndolesInterleukin-10MaleimidesPositive Regulatory Domain I-Binding Factor 1Proto-Oncogene Proteins c-mafSB 216763

Identifiers

PMID32817370
PMCPMC7477744
OpenAlexW3066330837

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.