Evidence map›Paper›PMID 32817346›Full record

ArticleMolecular & cellular proteomics : MCP2020

Analytical Guidelines for co-fractionation Mass Spectrometry Obtained through Global Profiling of Gold Standard

Chi Nam Ignatius Pang, Sara Ballouz, Daniel Weissberger, Loïc M Thibaut, Joshua J Hamey, Jesse Gillis, Marc R Wilkins, Gene Hart-Smith

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chi Nam Ignatius PangSystems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Sara BallouzGarvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia.
Daniel WeissbergerSchool of Chemistry, University of New South Wales, Sydney, New South Wales, Australia.
Loïc M ThibautSchool of Mathematics and Statistics, University of New South Wales, Sydney, New South Wales, Australia.
Joshua J HameySystems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Jesse GillisStanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Woodbury, New York, USA.
Marc R WilkinsSystems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Gene Hart-SmithSystems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia; Department of Molecular Sciences, Macquarie University, Sydney, New South Wales, Australia. Electronic address: gene.hart-smith@mq.edu.au.
UNSW Sydney · AUCold Spring Harbor Laboratory · USGarvan Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Co-fractionation MS (CF-MS) is a technique with potential to characterize endogenous and unmanipulated protein complexes on an unprecedented scale. However this potential has been offset by a lack of guidelines for best-practice CF-MS data collection and analysis. To obtain such guidelines, this study thoroughly evaluates novel and published

Indexed as

Chemical FractionationChromatography, GelChromatography, LiquidGene OntologyHumansMass SpectrometryProteomeProteomicsReference StandardsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsProteomeSaccharomyces cerevisiae ProteinsBioinformaticsChromatographyco-fractionation mass spectrometryProtein complex analysisprotein complexesprotein correlation profilingprotein-protein interactionsSaccharomyces cerevisiaeYeast*

Identifiers

PMID32817346
PMCPMC7664123
OpenAlexW3061482651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.