Evidence map›Paper›PMID 32817343›Full record

ArticleThe Journal of biological chemistry2020

Human ribosomal G-quadruplexes regulate heme bioavailability.

Santi Mestre-Fos, Chieri Ito, Courtney M Moore, Amit R Reddi, Loren Dean Williams

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. G-quadruplexes catalyze protein folding by reshaping the energetic landscape.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Fluorometric Methods to Measure Bioavailable and Total Heme.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  16. Gas-sensing riboceptors.RNA biology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. G-quadruplexes rescuing protein folding.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Santi Mestre-FosCenter for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, USA; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA; Parker Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Chieri ItoCenter for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, USA; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA; Parker Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Courtney M MooreSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA; Parker Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA.
Amit R ReddiSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA; Parker Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA. Electronic address: amit.reddi@chemistry.gatech.edu.
Loren Dean WilliamsCenter for the Origin of Life, Georgia Institute of Technology, Atlanta, Georgia, USA; School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA; Parker Petit Institute of Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, Georgia, USA; School of Biological Sciences, Georgia Institute of Technology, Atlanta, Georgia, USA. Electronic address: loren.williams@chemistry.gatech.edu.
Georgia Institute of Technology · US

Funding

Imaging heme based mitochondrial-cell signaling networks in cell and animal modelR33ES025661 · NIEHS · GEORGIA INSTITUTE OF TECHNOLOGY · PI REDDI, AMIT RAM · 2017 to 2019
$1.7M
Imaging heme based mitochondrial-cell signaling networks in cell and animal models of heavy metal toxicityR21ES025661 · NIEHS · GEORGIA INSTITUTE OF TECHNOLOGY · PI REDDI, AMIT RAM · 2015 to 2016
$416k
NIEHS NIH HHS R21 ES025661NIEHS NIH HHS R33 ES025661
6 · The paper itself

Abstract

The

Indexed as

G-QuadruplexesFluorescent Antibody TechniqueHEK293 CellsHemeHomeostasisHumansLigandsProtein BindingRibosomesRNA, RibosomalHemeLigandsRNA, RibosomalBG4expansion segmentsG4G-quadruplexG-tracthemeheminmetal homeostasisribosomal ribonucleic acid (rRNA) (ribosomal RNA)ribosomeRNAtentacle

Identifiers

PMID32817343
PMCPMC7606673
OpenAlexW3049092629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.